Protein NMR-based screening in drug discovery.

Curr Pharm Des

Department of Pharmaceutical Chemistry, School of Pharmacy, University of Maryland, Baltimore, 20 Penn Street, Baltimore, MD 21201, USA.

Published: December 2006

Protein NMR as a screening tool in drug discovery has become prominent within the past ten years. Advances in protein manipulation, whether by biological means (labeling) or physical means (NMR), have created a powerful method that is able to observe ligand-target interactions in solution.

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http://dx.doi.org/10.2174/138161206778743619DOI Listing

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