AI Article Synopsis
- The study assessed the anthelmintic (worm-killing) effects of condensed tannins (CT) in both lab tests and on lambs.
- In vitro tests showed that CT inhibited the hatching of worm eggs but did not affect adult worms, while in vivo tests revealed that lambs on CT diets had reduced egg counts in their feces.
- Overall, lambs fed with higher levels of CT (3%) experienced the greatest weight gain and improved nutrient utilization, suggesting that the benefits came from both direct and indirect effects of CT on the worms.
Article Abstract
Anthelmintic activity of condensed tannins (CT) was evaluated both in vitro and in vivo. In vitro tests included egg hatch test and paralysis/mortality assay on adult Haemonchus contortus. In vivo anthelmintic effect was determined by faecal egg count reduction test in lambs. To this end, 18 lambs were divided into three groups (low tannin, high tannin and control). The lambs of low and high tannin groups were fed diets containing 2 and 3% CT while the control group was fed on diets without CT. In vitro trials showed a dose-dependent inhibition of nematode egg hatching; whereas, there was no effect of CT on adult H. contortus. In vivo trials indicated reduction in faecal egg counts in lambs fed diets containing CT. Feed intake and nutrient digestibility of CT-fed sheep was lower and nitrogen balance was higher as compared to control. Maximum weight gain was observed in animals fed diets containing 3% CT. The direct anthelmintic effect of CT, therefore, was evidenced by inhibited egg hatching; whereas, faecal egg counts reduction in sheep was through improved nutrient utilization.
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| http://dx.doi.org/10.1016/j.vetpar.2006.09.035 | DOI Listing |
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