AI Article Synopsis
- A (31)P MRS study was conducted on the prefrontal cortex, basal ganglia, and superior temporal region in 10 children with ADHD and 15 healthy controls.
- ADHD patients showed significantly lower levels of phosphomonoesters in the prefrontal cortex and basal ganglia compared to their healthy peers, while no differences were found in the superior temporal region.
- These findings imply that children with ADHD may experience a reduction in membrane phospholipid precursor levels, indicating potential underdevelopment of neuronal structures and connections.
Article Abstract
This multi-voxel, phosphorus magnetic resonance spectroscopy ((31)P MRS) study examined the prefrontal cortex (PFC), basal ganglia (BG) and superior temporal (ST) region in 10 children with attention-deficit/hyperactivity disorder (ADHD) and 15 healthy controls. ADHD patients had lower PFC and BG phosphomonoester (PME) levels compared to healthy children. No differences were noted in the ST. These deficits in membrane phospholipid (MPL) precursor levels suggest reduced mass of cellular MPLs due to a possible underdevelopment of neuronal processes and synapses in ADHD.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.pscychresns.2006.08.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Trends in prescribing montelukast in patients with asthma in real-life: Results from the Turkish adult asthma registry.
Allergol Immunopathol (Madr)
January 2025
Department of Chest Disease, Division of Immunology and Allergy, Ankara University School of Medicine, Ankara, Turkey.
Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in asthma management remain limited. This registry-based study evaluated the use of montelukast in adult asthma patients, examining demographic and disease characteristics, asthma control status, asthma phenotypes, presence of atopy, and treatment regimens. Among 2053 patients analyzed, 61.
View Article and Find Full Text PDFApplying Natural Language Processing Techniques to Map Trends in Insomnia Treatment Terms on the r/Insomnia Subreddit: Infodemiology Study.
J Med Internet Res
January 2025
Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States.
Background: People share health-related experiences and treatments, such as for insomnia, in digital communities. Natural language processing tools can be leveraged to understand the terms used in digital spaces to discuss insomnia and insomnia treatments.
Objective: The aim of this study is to summarize and chart trends of insomnia treatment terms on a digital insomnia message board.
Maternal touch in object- and nonobject-oriented play interactions: A longitudinal study at 7 and 12 months.
Dev Psychol
January 2025
Psychological Neuroscience Lab, Psychology Research Center, School of Psychology, University of Minho.
Social touch is a crucial part of how mothers interact with their infants, with different touch types serving distinct purposes in these exchanges. However, there is still a limited understanding of how mothers' touch behavior adapts to specific interactive tasks, particularly throughout infancy. To address this gap, we observed mother-infant dyads at 7 and 12 months during three structured social play tasks: (a) play with objects, (b) play without objects, and (c) play with a difficult object.
View Article and Find Full Text PDFCOVID-19 Vaccine Hesitancy Among Black Women in the US.
JAMA Netw Open
January 2025
Department of Management, Policy, and Community Health, School of Public Health, The University of Texas Health Science Center, Houston.
Importance: COVID-19 vaccine hesitancy among Black women is a critical public health concern, potentially exacerbating existing health disparities and impacting community-wide vaccination efforts.
Objective: To explore the factors associated with COVID-19 vaccine hesitancy among Black women in the US and identify the specific concerns and experiences shaping hesitant attitudes toward vaccination.
Design, Setting, And Participants: Qualitative study using in-depth, semistructured interviews conducted virtually between June and November 2021.
PRMT1-Mediated Arginine Methylation Promotes Corneal Epithelial Wound Healing via Epigenetic Regulation of ANXA3.
Invest Ophthalmol Vis Sci
January 2025
State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Purpose: Protein arginine methyltransferase 1 (PRMT1) is an integral constituent of numerous cellular processes. However, its role in corneal epithelial wound healing (CEWH) remains unclear. This study investigates the impact of PRMT1 on cellular mechanisms underlying corneal epithelial repair and its potential to improve wound healing outcomes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!