Rapid small-scale column tests (RSSCTs) were employed to evaluate the impact of the dissolved oxygen (DO) concentration in the water used to create steam on the reactivation of spent granular activated carbon (GAC) using three novel thermal reactivation procedures: steam-curing, steam-curing with ramped temperature, and steam pyrolysis reactivation. Evaluation of the physical properties of the reactivated carbon showed a change in mass and volume loss with a change in DO. Performance testing of the carbons for removal of the taste- and odor-causing compound 2-methylisoborneol (MIB) showed that MIB uptake generally increased as the DO concentration decreased. Decrease in MIB removal with an increase in surface acidity, a phenomenon found in the literature, may be responsible for the changes in adsorption performance, as the higher DO concentrations yielded carbons with higher total surface acidity. In addition, the steam-curing process, which was implemented at 375 degrees C (i.e. about 400 degrees C lower than typical reactivation temperatures) with a low DO concentration (i.e. 3-4mg/L) had comparable performance to the virgin carbon counterpart, which could manifest cost-savings due to the low temperature associated with this protocol compared to conventional reactivation. Furthermore, since the mass loss associated with this steam-curing protocol was low, less virgin carbon make-up would be required also improving the economic viability of this reactivation protocol.
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http://dx.doi.org/10.1016/j.watres.2006.09.010 | DOI Listing |
Medicina (Kaunas)
November 2024
Department of GI Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
: Temperature-sensitive (TS) mutants of TP53 are thermally unstable, unfolded, and inactive at body temperature but can be refolded and reactivated at sub-physiological temperatures. TS TP53 may be amenable for functional rescue by hypothermia or structure-stabilizing drugs, and may retain low-level transcriptional activity at 37 °C. TP53 mutations are observed in 47% of all esophageal cancers (ECs) and 25% to 40% of gastric cancers (GCs).
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
Institute of Inorganic Chemistry, RWTH Aachen University, Landoltweg 1a, Aachen, 52074, Germany.
As a model for the energy-efficient aftertreatment of exhaust gas components, we studied microwave-assisted (MW) CO oxidation over a (La,Sr)CoO (LSC) perovskite oxide catalyst under dry and humidified conditions. We found that the use of a MW-based process can offer multiple advantages over traditional thermocatalysis in this scenario, as the nature of the MW-solid interaction offers quick, adaptive, and energy-efficient heating as well as improved yield and lower light-off temperatures. As found by combined CO and water MW-desorption experiments, the presence of technically relevant amounts of water leads to a competition for surface active sites and thus slows the reaction rate without indications for a fundamental change in the mechanism.
View Article and Find Full Text PDFACS Pharmacol Transl Sci
November 2024
Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, United States.
is commonly mutated in cancer, giving rise to loss of wild-type tumor suppressor function and increases in gain-of-function oncogenic roles. Thus, inhibition of mutant p53 and reactivation of wild-type function represents a potential means to target diverse tumor types. ()-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one (NSC59984), first identified from a high-throughput screen, induces wild-type p53 signaling and antiproliferative effects while inhibiting mutant p53 gain-of-function activities.
View Article and Find Full Text PDFFor Res (Fayettev)
August 2024
Canadian Forest Service, Natural Resources Canada, Great Lakes Forestry Centre, 1219 Queen Street East Sault Ste. Marie, P6A 2E5, ON, Canada.
Due to climate change, the timing of budbreak is occurring earlier in temperate and boreal tree species. Since the warmer conditions also cause snow to melt earlier in the spring, the hypothesis that bud reactivation of tree species of the mixedwood forests of Québec would occur under drier conditions in the future and that species from the temperate forests with late budbreak would be most exposed to dry conditions was tested. The thermal-time bud phenology model was used to predict the timing of budbreak for early and late species using 300 and 500 growing degree-days as the threshold for the timing of budbreak.
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