Unlabelled: We evaluated intra-rater, inter-rater, and between-scan reproducibility, hemispheric differences, and the effect of age on apparent diffusion coefficient (ADC) and fractional anisotropy (FA) in healthy children (age range 5.5-19.1 years) examined with a clinical diffusion tensor imaging (DTI) protocol at 1.5 T, using a region of interest (ROI) methodology. Measures of reliability and precision were assessed in six ROIs using two different ROI shapes (polygonal and ellipsoidal).

Results: Highly reproducible values of ADC and FA were obtained with the polygonal method on intra-rater (coefficients of variation

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1815474PMC
http://dx.doi.org/10.1016/j.neuroimage.2006.09.020DOI Listing

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