AI Article Synopsis
- This study explores how exercise impacts endothelial function and nitric oxide metabolism in dogs, looking at different breeds and the white-coat effect.
- Short bursts of exercise led to increased levels of plasma nitrate, nitrite, and von Willebrand factor, highlighting variations between breeds like Pointers and smaller breeds such as Cairn Terriers and Cavalier King Charles Spaniels.
- The study also found that plasma markers were affected by the environment, with higher levels in the lab compared to home settings, showing that exercise and context influence endothelial function in dogs.
Article Abstract
This study examines how systemic biomarkers of endothelial function and nitric oxide metabolism are affected by exercise in dogs. Furthermore, breed variation and white-coat effect have been tested by sampling three different dog breeds both in their home and in a clinical setting. Short-term exercise increased plasma nitrate and nitrite (NOx) and von Willebrand factor (vWf). There was significant difference between Pointers and the small dog breeds Cairn Terriers and Cavalier King Charles Spaniels in the general plasma levels of vWf and asymmetric dimethylarginine (ADMA). NOx and vWf were significantly higher when the sample was taken in the laboratory cf. at home, whereas ADMA and L-arginine were significantly lower. In conclusion, both short-term exercise and white-coat effect influence several plasma markers of endothelial function depending also on the breed and gender of the dogs. These findings should be considered in future studies concerning endothelial function in dogs.
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| http://dx.doi.org/10.1016/j.rvsc.2006.09.003 | DOI Listing |
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