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Cardioprotective potential of tectochrysin against vanadium induced heart damage via regulating NLRP3, JAK1/STAT3 and NF-κB pathway.

J Trace Elem Med Biol

January 2025

Department of Pathology, College of Medicine, King Khalid University, Asir 61421, Saudi Arabia; Department of Forensic Medicine and Clinical Toxicology, Mansoura University, Egypt.

Background: Vanadium (VAN) is a significant trace element, but its higher exposure is reported to cause severe organ toxicity. Tectochrysin (TEC) is a naturally derived flavonoid which demonstrates a wide range of pharmacological properties.

Aim: The current study was planned to assess the cardioprotective potential of TEC against VAN induced cardiotoxicity in rats via regulating biochemical, and histological profile.

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Most Mediterranean ecosystems have been profoundly shaped by wildfires, driving the evolution of plant species. Through photo interpretation and field inventories, this research assessed vegetation dynamics from 1984 to 2021, examining how fire severity and recurrence, key fire regime variables, influenced changes in structure and woody species diversity. Using two burn scars (1988 and 2006), we identified four scenarios dominated by Pinus pinea tree species: control (unburned), areas burned once (either in 1988 or 2006), and twice (in both 1988 and 2006).

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Coupling tree-ring and geomorphic analyses to reconstruct the 1950s massive Glacier Lake Outburst Flood at Grosse Glacier, Chilean Patagonia.

Sci Total Environ

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Climate Change Impacts and Risks in the Anthropocene (C-CIA), Institute for Environmental Sciences, University of Geneva, Geneva, Switzerland; dendrolab.ch, Department of Earth Sciences, University of Geneva, Geneva, Switzerland; Department F.-A. Forel for Environmental and Aquatic Sciences, University of Geneva, Switzerland.

Over recent decades, global warming has led to sustained glacier mass reduction and the formation of glacier lakes dammed by potentially unstable moraines. When such dams break, devastating Glacial Lake Outburst Floods (GLOFs) can occur in high mountain environments with catastrophic effects on populations and infrastructure. To understand the occurrence of GLOFs in space and time, build frequency-magnitude relationships for disaster risk reduction or identify regional links between GLOF frequency and climate warming, comprehensive databases are critically needed.

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Heavy metal(loid)s accumulation and human health risk assessment in wheat after long-term application of various urban and rural organic fertilizers.

Sci Total Environ

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Institute of Plant Nutrition, Resources and Environment, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China. Electronic address:

Composting urban and rural wastes into organic fertilizers for land application is considered the best way to dispose of and recycle waste resources. However, there are some concerns about the long-term effects of applying various organic fertilizers on soils, food safety, and health risks derived from heavy metal(loid)s (HMs). A long-term field experiment was conducted to evaluate the effects of continuous application of chicken manure compost (CM), sewage sludge compost (SSC), and domestic waste compost (DWC) for wheat on the accumulation, transfer, and health risks of HMs.

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Impact of water, sanitation, and hygiene indicators on enteric viral pathogens among under-5 children in low resource settings.

Sci Total Environ

January 2025

Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.

Poor water, sanitation, and hygiene (WASH) are the primary risks of exposure to enteric viral infection. Our study aimed to describe the role of WASH conditions and practices as risk factors for enteric viral infections in children under 5. Literature on the risk factors associated with all-cause diarrhea masks the taxa-specific drivers of diarrhea from specific pathogens, limiting the application of relevant control strategies.

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