[Regulon in the treatment of hyperandrogenism in teenage girls].

Unlabelled: The aim of study was to assess the efficiency of the use of combined oral contraceptive with dezogestrel-regulon in the treatment of hyperandrogenism in teenage girls. 14-18 y.o. girls with signs of hyperandrogenism have been investigated. Investigation included: physical examination, assessment of body mass, hirsute number, ultrasonography, FSH, LH, prolactin, testosterone, 17 OH progesterone in blood.

Results: All the patients received Regulon from the 5th up to 21st day of menstrual cycle during 6 months. After the 6 months of treatment the regulation of menstrual cycle have been registered in 91% of patients. Reduction of hirsute number (from 24.1+/-1.0 to 11.0+/-1.2 ), ovarian volume by ultrasound (from 16.7+/-3.0 sm(3) to 7.1+/-0.9 sm(3)), level of LH (from 12.7+/-2.4 to 8.0+/-1.2 IU/L) and testosterone (from 4.2 +/-0.2 to 2.8+/-0.6 nmol/l) were registered. Regulon is effective for the treatment of hyperandrogenism in teenage girls.