A series of pyridine ether PPAR agonists were synthesized through an ADDP and PS-PPh3 modified Mitsunobu protocol, which eliminated significant by-product formation. This method proved to be versatile, efficient and amenable to parallel synthesis.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705810 | PMC |
http://dx.doi.org/10.1186/1860-5397-2-21 | DOI Listing |
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