This in vitro study investigated the relationship between assessments of dentin caries using a laser fluorescence device (DIAGNOdent) and a caries detector dye during caries removal. The dentin of eight extracted carious molars was removed at 300-microm interval points from the dentin surface toward the pulp chamber. Before and after each removal, images of the carious surfaces were taken in association with color-matching stickers (for color correction) and the surfaces were evaluated by DIAGNOdent based on fluorescence emission from the tooth surface. For the L* values (CIE 1976 L*a*b* color system), there was a strong negative correlation between DIAGNOdent results and the corrected L* values of the carious surfaces (Pearson's correlation coefficient: -0.853); additionally, there was a significant correlation between them (p<0.05). However, there were no significant correlations between the DIAGNOdent results and the corrected a* and b* values of the carious surfaces (Pearson's correlation coefficients: 0.108 and 0.018 respectively). In conclusion, DIAGNOdent was shown to be applicable for caries diagnosis during caries removal.
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http://dx.doi.org/10.4012/dmj.25.584 | DOI Listing |
Int J Nanomedicine
December 2024
State Key Laboratory of Ophthalmology, Optometry and Visual Science, National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
Background: Developing carrier-free nanomedicines via self-assembly of two antitumor drug molecules is a potential strategy for enhancing the combination treatment of tumors. Similarly, conventional chemotherapy combined with photodynamic therapy may synergistically improve the antitumor effect while minimizing the adverse reactions associated with antitumor treatment. Hyaluronic acid (HA) can bind to overexpressed HA receptors on the tumor cell surface, increasing cell internalization and resulting in good tumor-targeting properties.
View Article and Find Full Text PDFLasers Med Sci
January 2025
Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157th Xi 5 Road, Xi'an, 710004, PR China.
Non-tuberculous mycobacterial skin infection lead to complex and lengthy treatment cycles. Antimicrobial photodynamic therapy (aPDT) is an emerging promising approach for treating infections. This study aims to assess the effects of aPDT using curcumin as a photosensitizer (PS) on non-tuberculous mycobacteria, Mycobacterium abscessus, a subtype that has become common in dermatology in recent years.
View Article and Find Full Text PDFBDJ Open
January 2025
Professor of Conservative Dentistry, Faculty of Dentistry, Cairo University, Giza, Egypt.
Objectives: To assess the validity of light-induced and laser-induced fluorescence devices compared to the visual-tactile method for detecting secondary caries around resin composite restorations.
Materials And Methods: The study included 20 participants with 30 resin-composite restored teeth. Restorations' margins were examined using three diagnostic methods: the visual-tactile method (FDI criteria), the light-induced fluorescence camera (VistaCam iX), and the laser-induced fluorescence device (DIAGNOdent pen), and the reference was visual inspection after removal of defective restorations.
Ann Gastroenterol Surg
January 2025
Radical lymphadenectomy is the critical component of surgery for esophageal cancer. However, lymphadenectomy significantly contributes to postoperative morbidity, particularly in terms of pulmonary complications following esophagectomy. Function-preserving mediastinal lymphadenectomy seeks to balance the procedure's necessary radicality and optimal functional outcomes.
View Article and Find Full Text PDFRSC Adv
January 2025
Nanoscience Program, Institute of Basic and Applied Sciences, Egypt-Japan University of Science and Technology New Borg El-Arab City Alexandria Egypt
We report herein a facile synthesis, characterization, and the electron transfer reaction of a novel light-harvesting material composed of laser-induced graphene (LIG) functionalized with the photoactive 5,10,15,20-tetrakis(4-trimethylammoniophenyl)porphyrin tetra(-toluenesulfonate) dye (TTMAPP). LIG was easily fabricated on the surface of a polyimide sheet using VersaLASER 3.6 (VLS 3.
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