Objective: To raise awareness between laparoscopists about umbilical endometriosis and to recommend the appropriate management measure for this rare but easily treatable condition.
Design: Case reports and literature review.
Setting: Women presented to general surgeon with umbilical masses.
Patient(s): Women of reproductive age with histologic diagnosis of umbilical endometriosis.
Intervention(s): Excision with histopathologic examination.
Main Outcome Measure(s): Definite diagnosis and clinical improvement.
Result(s): Umbilical endometriosis is best diagnosed and cured with excisional biopsy. Other diagnostic methods have been proven to be nonspecific and unreliable in the literature.
Conclusion(s): Clinical diagnosis of this condition can be difficult even with the aid of cytology and imaging. Surgical excision with removal and histopathology is recommended for both diagnostic and therapeutic purposes. Simultaneous laparoscopy should be recommended to the patient with suspected pelvic endometriosis.
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http://dx.doi.org/10.1016/j.fertnstert.2006.03.070 | DOI Listing |
Radiol Case Rep
February 2025
Faculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Int Med Case Rep J
December 2024
Gynecology and Obstetric Department, Kabul University of Medical Science, Shahr Ara University Hospital, Kabul, Afghanistan.
Primary umbilical endometriosis is a rare condition in which there is endometrial glands and stroma in the umbilicus. Primary umbilical endometriosis is also called villar's nodule. This condition is a diagnostic challenge, the pathophysiology of the disease is not well defined and should be considered in all other pathologies of the umbilicus.
View Article and Find Full Text PDFRare Tumors
September 2024
Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria.
Proc Natl Acad Sci U S A
September 2024
Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.
Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in nonhormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role in the pathophysiology of endometriosis and represent a promising therapeutic target.
View Article and Find Full Text PDFJ Mol Med (Berl)
November 2024
Department of Gynaecology, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.
Endometriosis is a multifactorial gynecological disease, with angiogenesis as a key hallmark. The role of exosomal microRNAs (miRNAs) in endometriosis is not well understood. This study investigates differentially expressed exosomal miRNAs linked to angiogenesis in endometriosis, clarifies their molecular mechanisms, and identifies potential targets.
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