Posterior cortical atrophy: a brief review.

Curr Neurol Neurosci Rep

Department of Neurology, Vanderbilt University School of Medicine, 2311 Pierce Avenue, Nashville, TN 37232-3375, USA.

Published: November 2006

AI Article Synopsis

  • Posterior cortical atrophy starts with visual symptoms before progressing to more complex issues like visual agnosia and spatial disorientation.
  • Over time, patients may exhibit symptoms of Balint's syndrome and Gerstmann's syndrome, which affect reading, writing, and basic cognitive functions.
  • The condition can be linked to various underlying neuropathological disorders and may also include hallucinations and signs associated with Parkinson's disease or Lewy body dementia.

Article Abstract

Posterior cortical atrophy is a striking clinical syndrome in which a dementing illness begins with visual symptoms. Initially, the problem may seem to be loss of elementary vision, but over time the patient develops features of visual agnosia, topographical difficulty, optic ataxia, simultanagnosia, ocular apraxia (Balint's syndrome), alexia, acalculia, right-left confusion, and agraphia (Gerstmann's syndrome), and later a more generalized dementia. Occasional patients have visual hallucinations and signs of Parkinson's disease or Lewy body dementia. A number of different neuropathologic disorders are associated with posterior cortical atrophy.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11910-006-0049-0DOI Listing

Publication Analysis

Top Keywords

posterior cortical
12
cortical atrophy
12
atrophy review
4
review posterior
4
atrophy striking
4
striking clinical
4
clinical syndrome
4
syndrome dementing
4
dementing illness
4
illness visual
4

Similar Publications

Lens tension is essential for accommodative vision but remains challenging to measure with precision. Here, we present an optical coherence elastography (OCE) technique that quantifies both the tension and elastic modulus of lens tissue and capsule. This method derives mechanical parameters from surface wave dispersion across a critical frequency range of 1-30 kHz.

View Article and Find Full Text PDF

In sensory and mid-level regions of the brain, stimulus information is often topographically organized; functional responses are arranged in maps according to features such as retinal coordinates, auditory pitch, and object animacy or size. However, such organization is typically measured during stimulus input, e.g.

View Article and Find Full Text PDF

Anhedonia, a core symptom of depression, has been defined as the loss of pleasure or lack of reactivity to pleasurable stimuli. Considering the relevance of alpha asymmetry to MDD and anhedonia, we explored the effect of dorsolateral prefrontal cortex (DLPFC) stimulation on frontal and posterior EEG alpha asymmetry (FAA and PAA, respectively), in this exploratory investigation. 61 participants randomly received sham (n = 11), bilateral (BS; n = 25), or unilateral stimulation (US; n = 25) of the DLPFC.

View Article and Find Full Text PDF

Baseline gray matter volume associates with working memory performance after prefrontal transcranial direct current stimulation.

Behav Brain Res

January 2025

Department of Head and Skin, Psychiatry and Medical Psychology, Ghent University Hospital, Ghent University, Ghent, Belgium; Ghent Experimental Psychiatry (GHEP) Lab, Ghent University, Ghent, Belgium. Electronic address:

Working memory is crucial for daily life and is often impaired in neuropsychiatric conditions. Attempts to enhance it using transcranial direct current stimulation (tDCS) have shown mixed results, possibly due to large inter-individual variability. This study assessed whether baseline regional brain volume was associated with working memory performance following tDCS.

View Article and Find Full Text PDF

Aberrant Cortical Morphological Networks in First-Episode Schizophrenia.

Schizophr Bull

January 2025

Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou 510631, China.

Background And Hypothesis: Population-based morphological covariance networks are widely reported to be altered in schizophrenia. Individualized morphological brain network approaches have emerged recently. We hypothesize that individualized morphological brain networks are disrupted in schizophrenia.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!