Surgical treatment of pararenal aortic aneurysms, if compared to open surgical repair of infrarenal aneurysms, is technically more demanding and characterized by problems related to organ ischemia. To better define challenges, risks, and results, we analyzed our experience with the treatment of pararenal aortic aneurysms. Between January 1993 and March 2005, 119 consecutive patients underwent surgery for pararenal aneurysms at our institution. A prospective analysis of results was performed. According to their localization, we treated 85 juxtarenal aneurysms and 34 suprarenal aneurysms. One hundred and three patients underwent primary repair of an atherosclerotic aneurysm, four patients underwent surgical repair of an anastomotic pseudoaneurysm, and eight patients underwent correction of an aneurysm of the pararenal aorta proximal to a previous infrarenal anastomosis. Four patients underwent emergency operation for a ruptured aneurysm. In the juxtarenal aneurysm group, the 30-day mortality rate was 4.7% (4/85) including three patients with ruptured aneurysm. In the suprarenal aneurysm group, the 30-day mortality rate was 2.9% (1/34). Preoperative renal insufficiency was present in 16 patients, respectively in 7 patients with juxtarenal aneurysms and in 9 patients with suprarenal ones. In 22 patients, we registered a transient increase in creatinine levels with return to baseline levels by discharge. Four patients required long-term dialysis. In three patients, a short period of dialysis was required. Clamping time longer than 30 min was associated with a higher risk of transient postoperative deterioration of renal function (p = 0.0073). Preoperative renal insufficiency was associated with a higher risk of persistent postoperative deterioration of renal function (p < 0.0001). Morbidity and mortality of elective surgery for pararenal aneurysms is acceptable. One of the main risks of this surgery is renal morbidity. Preoperative renal insufficiency and long periods of renal ischemia are associated with a higher risk of postoperative deterioration of renal function that is often, but not always, reversible. Nowadays, pararenal aneurysm repair is a safe procedure, especially if performed electively.
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Germs
September 2024
MD, PhD, Professor, Department of Orthopedics, Carol Davila University of Medicine and Pharmacy, No. 8 Eroii Sanitari Boulevard, Bucharest, 050474, Romania.
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February 2025
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China.
The present study aimed to determine the potential of carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), carbohydrate antigen (CA)19-9 and CA242 in predicting recurrence/metastasis of gastric cancer in patients following radical gastrectomy. The clinical data of 368 patients with stage I-III gastric cancer who underwent radical gastrectomy were analyzed, and CEA, AFP, CA19-9 and CA242 levels were detected prior to surgery and 6-12 months following surgery. Univariate and multivariate analyses were used to evaluate the potential risk factors for post-operative recurrence/metastasis of gastric cancer, and the predictive value of CEA, AFP, CA19-9 and CA242 levels was evaluated using receiver operating characteristic (ROC) curve and area under the curve (AUC).
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February 2025
Department of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan.
Currently, neoadjuvant chemotherapy (NAC) is usually performed even for resectable pancreatic ductal adenocarcinoma (rPDAC). The present study investigated the benefits of NAC with gemcitabine plus S-1 for rPDAC. The medical records of 170 patients diagnosed as having rPDAC based on preoperative imaging were reviewed retrospectively.
View Article and Find Full Text PDFActa Cardiol Sin
January 2025
School of Medicine, National Yang Ming Chiao Tung University.
Acta Cardiol Sin
January 2025
Department of Biomedical Engineering, National Taiwan University, Taipei.
Background: Prompt primary percutaneous coronary intervention (pPCI) is crucial for the prognosis and reduction of myocardial damage in ST-segment elevation myocardial infarction (STEMI) patients. The Coronavirus Disease 2019 (COVID-19) pandemic had multifaceted impacts on healthcare. This study assessed the effects of the pandemic on pPCI procedures and clinical outcomes in emergency STEMI patients.
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