We have recently described a revised scheme for spermatogonial expansion in non-human primates. We proposed that A(pale)-spermatogonia act as self-renewing progenitors and premeiotic germ cells are organized and divide as small clones. Here, we are revisiting the model described for man and propose a modified scheme for spermatogonial expansion. Our revised model shows high similarity to the scheme proposed for non-human primates and is in accordance with all previous and present data.
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| http://dx.doi.org/10.1530/rep.1.01081 | DOI Listing |
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