Background: People with traumatic brain injury (TBI) must often deal with cognitive problems, including social problem-solving. The study reported herein evaluated the effectiveness of a newly developed pictorial-based analogical problem-solving skills training programme. It is hypothesized that the programme can help people with TBI to learn better problem-solving skills through systematic, theoretically driven learning strategies.
Method: Based on the instrumental enrichment model and the hierarchy of daily problem-solving as suggested by Holloran and Bressler, analogical problem-solving training software was developed. Thirty subjects with TBI then attended a 20-session interactive analogical problem-solving skills training programme. Another 20 subjects with TBI and of similar demographics formed the control group. The outcome measures included session-based quizzes on analogical problem-solving, the Category Test of the Halstead Reitan Test Battery (HRTB) and the Lawton IADL Scale.
Findings: The analogical problem-solving training strategies were found to be effective in improving problem-solving skills. The subjects generally demonstrated a selective improvement in their functional and overall problem-solving skills, but not in their basic problem-solving skills. The subjects in the control group showed stable problem-solving skills over a 4-week interval (no statistically significant changes). The findings indicated the therapeutic significance of the training programme.
Conclusions: The results of the study suggested that innovative cognitive rehabilitation programmes can be customized to match the needs of clients with TBI. The applicability and implications of the interactive pictorial-based analogical problem-solving skill-training programme that was used in the study and possibilities for future study in this research area are also discussed.
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http://dx.doi.org/10.1080/13561820600909852 | DOI Listing |
Neurogenetics
January 2025
Department of Biochemistry, College of Medicine, University of Lagos, Lagos State, Nigeria.
Schizophrenia (SZ) is a complex, chronic mental disorder characterized by positive symptoms (such as delusions and hallucinations), negative symptoms (including anhedonia, alogia, avolition, and social withdrawal), and cognitive deficits (affecting attention, processing speed, verbal and visuospatial learning, problem-solving, working memory, and mental flexibility). Extensive animal and clinical studies have emphasized the NMDAR hypofunction hypothesis of SZ. Glycine plays a crucial role as an agonist of NMDAR, enhancing the receptor's affinity for glutamate and supporting normal synaptic function and plasticity, that is, signal transmission between neurons.
View Article and Find Full Text PDFNat Prod Rep
December 2024
Department of Medicinal Chemistry and Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, 1345 Center Drive, Gainesville, Florida 32610, USA.
Covering 2010-April 2024There have been tremendous new discoveries and developments since 2010 in anticancer research based on marine cyanobacteria. Marine cyanobacteria are prolific sources of anticancer natural products, including the tubulin agents dolastatins 10 and 15 which were originally isolated from a mollusk that feeds on cyanobacteria. Decades of research have culminated in the approval of six antibody-drug conjugates (ADCs) and many ongoing clinical trials.
View Article and Find Full Text PDFJ Sleep Res
November 2024
Department of Psychology, Texas State University, San Marcos, Texas, USA.
In analogical problem solving, the solution to a previously experienced problem (source) is used to solve a new but structurally similar problem (target). Yet, analogical transfer is seldom successful, as structural commonalities between source and target problems can be difficult to recognise. Theoretically, memory consolidation processes during REM sleep may help to identify and strengthen connections between weakly related memories, improving the ability to use analogical transfer.
View Article and Find Full Text PDFSci Rep
November 2024
Department of Linguistics, University of Iowa, Iowa, USA.
Every day, listeners encounter a wide range of acoustic signals. Successfully solving this variability problem allows them to interpret these signals accurately. While this mechanism tends to be less effortful for adults, children need to learn stable categories in the face of such variability.
View Article and Find Full Text PDFQ J Exp Psychol (Hove)
December 2024
Department of Psychology, Binghamton University, State University of New York, Binghamton, NY, USA.
The ability to spontaneously access knowledge of relational concepts acquired in one domain and apply it to a novel domain has traditionally been explored in the analogy literature via the problem-solving paradigm. In the present work, we propose a novel procedure based on categorisation as a complementary approach to assess spontaneous analogical transfer-using one category learning task to enhance learning of the same underlying category structures in another domain. In Experiment 1, we demonstrate larger improvements in classification performance across blocks of training in a target category learning task among participants that underwent a base category learning task relative to a separate group of participants learning the target category structures for the first time, thus providing evidence for spontaneous transfer of the category structures.
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