Coxiella burnetii, the agent of Q fever in humans, has been associated with abortion in cattle. In this study 650 sera from cattle with abortion and 600 randomly-selected control sera were examined for antibodies to C. burnetii by ELISA. Two hundred and ninety-two (44.9%) out of 650 animals which experienced abortion were seropositive versus 132 (22%) out of 600 of the control group. A statistically significant difference resulted from the comparison of the seroprevalence of aborted cattle with that of controls (p < 0.001). Moreover, a significant higher prevalence was disclosed in cattle which aborted during late gestation (p < 0.002) and in the autumn (p < 0.001).
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Heliyon
December 2024
Qinghai University State Key Laboratory of Plateau Ecology and Agriculture, Xining, 810016, Qinghai, China.
The Qinghai Lake National Nature Reserve (QLNNR), renowned for its abundant natural resources and diverse ecological habitats, serves as an ideal environment for ticks, thereby increasing the risk of various tick-borne pathogens (TBPs) transmission. This study aimed to investigate the prevalence of TBPs in ticks collected from Przewalski's gazelle and Tibetan sheep within the QLNNR. A total of 313 tick samples were collected from the vicinity of Qinghai Lake.
View Article and Find Full Text PDFOne Health
December 2024
One Health Research Group, Facultad de Ciencias de la Salud, Universidad de Las Américas, Quito, Ecuador, 170503.
Q fever, caused by the bacterium , is a zoonotic disease that has been largely overlooked despite presenting significant risks to both animal and public health. Although well studied in some countries, in most countries in Latin America, there's a lack of information on infection, its prevalence, and its impact on both livestock and human populations. To address this gap, we conducted a serosurvey among farm workers, cattle, sheep, and dogs on two dairy farms in Ecuador using a commercial ELISA kit.
View Article and Find Full Text PDFBMC Vet Res
December 2024
Friedrich-Loeffler-Institut, Institute of Bacterial Infections and Zoonoses, 07743, Jena, Germany.
This study aimed to assess the geographical distribution of Q fever in sheep and goats in different areas of Punjab, Pakistan. Three hundred blood samples of small ruminants including sheep and goats were collected from 60 villages of three districts (Okara, Kasur, and Pakpattan) of Punjab Province Pakistan and tested for the detection of anti-Coxiella burnetii antibodies using a commercial Indirect ELISA kit. Data related to sampling location, host species, gender, age, and GPS coordinates were collected for spatial analysis.
View Article and Find Full Text PDFRes Sq
December 2024
Department of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA.
(Cb), the causative agent of Q fever, replicates within host macrophages by modulating immune responses through poorly understood mechanisms. Long non-coding RNAs (lncRNAs) are emerging as critical regulators of inflammation, yet their role in Cb pathogenesis remains largely unexplored. Here, we employed a global transcriptomic approach to identify lncRNAs specific to Cb infection in THP-1 derived macrophages, compared to 15 other microbial infections.
View Article and Find Full Text PDFEpidemiol Infect
December 2024
Department of Virology, Veterinary Faculty, Necmettin Erbakan University, Konya, Türkiye.
Abortion is one of the major threats to the livestock industry, and it also poses significant threats to public health since some of the abortifacient agents are considered zoonotic. (), (), (), and Cache Valley virus (CVV) are recognized as important zoonotic and abortifacient agents of reproductive failure in small ruminants. This study determined the prevalence of these agents in ovine and caprine foetuses in Türkiye.
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