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Fixation Stability Deficits in Anisometropic Amblyopia.

Invest Ophthalmol Vis Sci

January 2025

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-Sen University, Guangzhou, China.

Purpose: The purpose of this study was to investigate the relationship between fixation stability deficits in anisometropic amblyopia and various visual functions, as well as the underlying retinal structure.

Methods: All 164 patients with anisometropic amblyopia were recruited in this cross-sectional study. The contrast sensitivity function (CSF) was measured using the qCSF method, whereas the MP-3 microperimeter was used to assess fixation stability and locate the preferred retinal locus.

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Aim: To compare relative peripheral refractive errors (RPREs) in Chinese children with and without myopic anisometropia (MAI) and to explore the relationship between RPRE and myopia.

Methods: This observational cross-sectional study included 160 children divided into two groups according to the interocular spherical equivalent refraction (SER) difference ≥1.0 D in the MAI group (=80) and <1.

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Multiple Factors Causing Variability of Alignment in Childhood Concomitant Strabismus.

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February 2025

From the Department of Ophthalmology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Key Laboratory of Major Diseases in Children, Ministry of Education (Y.G., Y.G., L.L., J.J.), Beijing, China. Electronic address:

Article Synopsis
  • The study aimed to identify factors affecting alignment variability in children with concomitant strabismus, which includes conditions like esotropia and exotropia.
  • It involved 197 children undergoing repeated tests by certified orthoptists, determining alignment stability based on measurement differences of less than 10 prism diopters.
  • Results indicated that suppression and anisometropia significantly influence measurement variability, and larger angles of strabismus correlate with greater alignment variability, especially at a distance.
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Refractive errors in Tianjin youth aged 6-18 years: exploring urban-rural variations and contributing factors.

Front Med (Lausanne)

September 2024

Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.

Article Synopsis
  • This study investigates the prevalence and risk factors of refractive errors (myopia, hyperopia, etc.) among youth in urban and rural Tianjin, China, highlighting the importance of understanding these differences for public health initiatives.
  • Conducted in 2022, the study involved over 346,000 students aged 6-18 from both environments who underwent visual testing and filled out questionnaires.
  • Findings indicate that urban students are more likely to have myopia but less likely to have hyperopia compared to their rural peers, with factors such as age, near-work activities, and outdoor time contributing to these differences.
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  • * The Spot Vision Screener was used to evaluate 714 children for amblyopia risk factors, leading to 84 referrals, with ophthalmologists confirming amblyopia in 65 cases.
  • * The research emphasizes the need for effective vision screening programs in rural areas to help detect and manage amblyopia early, ultimately reducing childhood blindness.
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