A cell permeable DPP II [also known as DPP2, DPP7, and quiescent cell proline dipeptidase (QPP)] inhibitor has been synthesized. The azabicyclo[3.3.0]octane-based inhibitor is potent and selective and elicits very similar quiescent lymphocyte death to previously characterized inhibitors that are not as selective.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828633 | PMC |
http://dx.doi.org/10.1016/j.bmcl.2006.10.012 | DOI Listing |
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