Eat the meat or feed the meat: protein turnover in remodeling muscle.

Curr Opin Clin Nutr Metab Care

Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Department of Movement Sciences, Maastricht University, 6200 MD Maastricht, the Netherlands.

Published: November 2006

AI Article Synopsis

  • The review discusses how muscle protein turnover is key for muscle remodeling, focusing on nutrition and exercise impacts.
  • Recent advancements have enhanced the understanding of the processes regulating protein synthesis and degradation in muscles, indicating that they adapt to various demands.
  • For effective muscle remodeling, both the timing and type of nutrition and exercise are important.

Article Abstract

Purpose Of Review: The present review outlines the role of muscle protein turnover in muscle remodeling, with emphasis on the effects of nutrition and exercise.

Recent Findings: Progress in our understanding of the pathways signaling and regulating protein synthesis and degradation, and thus protein turnover, in skeletal muscle has been substantial over the past decade. Protein synthesis and degradation jointly allow the active remodeling of skeletal muscle to adapt to changes in mechanical and metabolic demand. Nutrition and exercise are potent ways to stimulate protein turnover. This occurs in an amino acid and exercise-type (resistance versus endurance) and mode (lengthening and shortening)-specific manner.

Summary: For optimal muscle remodeling, the timing and type of feeding and exercise appear to be crucial.

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Source
http://dx.doi.org/10.1097/01.mco.0000247471.64532.7dDOI Listing

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