Solid-cystic (papillary-cystic) tumours (SCT) of the pancreas are distinctive neoplasms with a predilection for young female patients. This is the first detailed report describing the occurrence of SCT in two young male patients. Except for the extapancreatic occurrence of one of the tumours (in the retroperitoneal region behind the head of the pancreas), all other clinicopathological features were identical to those characterizing the SCT in women. Immunostaining was (at least focally) positive for Lu 5 (broad spectrum keratin marker), vimentin and alpha-1-antitrypsin. The tumours were negative for neuroendocrine markers (except for neuron-specific enolase), pancreatic hormones and enzymes, pancreatic stone protein, carcinoembryonic antigen, CA 19-9 and nuclear oestrogen and progesterone receptors. This report does not support the suggested female sex hormone dependence of SCT.
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http://dx.doi.org/10.1007/BF01600295 | DOI Listing |
J Gastrointest Surg
March 2008
Department of Pathology, Emory University, Atlanta, GA 30322, USA.
In contrast with solid tumors, most of which are invasive ductal adenocarcinoma with dismal prognosis, cystic lesions of the pancreas are often either benign or low-grade indolent neoplasia. Those that are mucinous, namely, intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs), constitute the most important category, not only because they are the most common, but more importantly because they have well-established malignant potential, representing an adenomacarcinoma sequence. While many are innocuous adenomas--in particular, those that are small and less complex, and in the case of IPMN, those that are branch-duct type are more commonly benign, some harbor or progress into in situ or invasive carcinomas.
View Article and Find Full Text PDFRev Gastroenterol Mex
November 2002
Departamento de Cirugía, American British Cowdray Medical Center IAP, México, D.F.
Objective: To report an infrequent case of pancreatic pseudopapillary solid-cyst tumor, known as Frantz tumor, discovered after blunt abdominal trauma, and to carry out a review of the literature.
Background: Frantz's tumor is a very uncommon low-grade malignant papillary-cystic neoplasm of the pancreas that is relatively frequent in young black women and was first described by Frantz in 1959.
Case Report: We present the case of a 15-years-old female patient who, 24 h after blunt abdominal trauma, came to the emergency room with intense abdominal and atypical pain and a palpable mass in the left upper quadrant.
The case of an 8-year-old girl with pancreatic papillary cystic tumor is described. The patient presented chronic abdominal pain as the sole symptom. Abdominal ultrasound showed a pancreatic mass; computed tomography (CT) and magnetic resonance (MR) evidenced tumoral location in pancreatic body and tail, which was surgically removed.
View Article and Find Full Text PDFRev Med Chil
July 1994
Servicio de Radiología y Anatomía Patológica, Hospital San Juan de dios, Facultad de Medicina, Universidad de Chile, Hospital San Juan de Dios, Santiago de Chile.
Papillary cystic tumor of the pancreas is a rare low grade carcinoma, with only 130 cases reported in the English literature. We report a 22 years old female presenting with a palpable mass and abdominal pain. Abdominal ultrasound and CAT scan showed a solid-cystic lesion in the head of the pancreas.
View Article and Find Full Text PDFLangenbecks Arch Chir
November 1993
Chirurgische Klinik mit Poliklinik, Universität Erlangen-Nürnberg.
Before 1978, where cystic tumors of the pancreas were concerned, pathologists only differentiated between cystic adenomas and cystadenocarcinomas. Recently, however, further tumor entities have been introduced. We now differentiate between the generally benign serous cystic adenoma, the potentially malignant mucinous cystadenoma, the possibly malignant papillary cystic tumor, and the always malignant mucinous cystadenocarcinoma.
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