Measurements of total body calcium by prompt-gamma neutron activation analysis using a 252Cf source.

Biol Trace Elem Res

Department of Medical Physics, Clinical Engineering, Singleton Hospital, Swansea, Wales, UK.

Published: March 1991

A clinical neutron activation instrument has been developed for in vivo elemental analysis. Utilizing the prompt-capture gamma ray technique, simultaneous total body (TB) measurements of primarily Ca, but also Cl, N, C, and H are routinely performed. This paper describes a technique for the measurement of TBCa (g) that relies on the use of TBCl as an internal standard. The method has been tested with four anthropomorphic phantoms covering a range of body habitus. The mean discrepancy between the measured and known Ca contents was 3.6%. The technique has been applied to two patient groups, and encouraging results were obtained.

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http://dx.doi.org/10.1007/BF02992698DOI Listing

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