Background: Multiple chemical sensitivity (MCS) has an estimated American prevalence of 15%, and no consistently abnormal laboratory tests are available to assist in its diagnosis. Some physicians treating MCS patients have observed changes in intra-erythrocytic minerals (IEMs). As co-factors, minerals could influence detoxication of xenobiotics.
Aim: To test whether IEM differed comparing MCS cases with controls.
Methods: A total of 408 women meeting validated inclusion and exclusion criteria for MCS participated in this case-control study.
Results: No statistically significant differences were observed. However, for copper, chromium, magnesium, molybdenum, sulphur and zinc, mean detectable levels were all lower in cases. No dose-response relationships were found.
Conclusion: IEM measurements do not appear to provide useful diagnostic markers for MCS.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/occmed/kql104 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques.
Viruses
December 2024
Gilead Sciences, Inc., Foster City, CA 94404, USA.
Ebola virus (EBOV) causes severe disease in humans, with mortality as high as 90%. The small-molecule antiviral drug remdesivir (RDV) has demonstrated a survival benefit in EBOV-exposed rhesus macaques. Here, we characterize the efficacy of multiple intravenous RDV dosing regimens on survival of rhesus macaques 42 days after intramuscular EBOV exposure.
View Article and Find Full Text PDFFormulating a Horseradish Extract in Phospholipid Vesicles to Target the Skin.
Pharmaceutics
November 2024
Department of Life and Environmental Sciences, University of Cagliari, S.P. Monserrato-Sestu km 0.700, 09042 Cagliari, Italy.
: Horseradish ( L.) roots-largely used in traditional medicine for their multiple therapeutic effects-are a rich source of health-promoting phytochemicals. However, their efficacy can be compromised by low chemical stability and poor bioavailability.
View Article and Find Full Text PDFFlexible PAN/P25 Multi-Porous Nanotubular Electrospun Membrane Constructed by a Facile Ethylene Glycol Solvothermal Induction with Excellent Photocatalytic Degradation and Sterilization Performance.
Polymers (Basel)
December 2024
Hubei Three Gorges Laboratory, Yichang 443000, China.
A series of flexible polyacrylonitrile/TiO (PAN/P25) multi-porous nanotubular membranes were successfully constructed by facile electrospinning combined with an ethylene glycol solvothermal induce strategy. The effects of P25 dosage and solvothermal time on the morphology of samples were systematically investigated, which were characterized in terms of surface morphology, microstructure, specific surface area, thermal analysis, wettability, photoelectrochemical and fluorescence spectra. Rhodamine B (RhB) and () were employed as simulated pollutants to evaluate photocatalytic degradation and antibacterial properties of the PAN/P25-3 multi-porous nanotubular membrane.
View Article and Find Full Text PDFBioconversion of Food and Green Waste into Valuable Compounds Using Solid-State Fermentation in Nonsterile Conditions.
Plants (Basel)
December 2024
Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.
Agro-industrial residues have transitions from being an environmental problem to being a cost-effective source of biopolymers and value-added chemicals. However, the efficient extraction of the desired products from these residues requires pretreatments. Fungal biorefinery is a fascinating approach for the biotransformation of raw materials into multiple products in a single batch.
View Article and Find Full Text PDFAn Integrated Testing Strategy and Online Tool for Assessing Skin Sensitization of Agrochemical Formulations.
Toxics
December 2024
Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli 35053, Taiwan.
Non-animal assessment of skin sensitization is a global trend. Recently, scientific efforts have been focused on the integration of multiple evidence for decision making with the publication of OECD Guideline No. 497 for defined approaches to skin sensitization.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!