Amyopathic dermatomyositis is a rare condition. We describe the clinical and histopathologic findings of a 53-year-old woman who developed cutaneous lesions similar to those described in dermatomyositis after fibrate therapy for hypertriglyceridemia. Our patient fits the proposed criteria for amyopathic dermatomyositis, and after 8.5 years, muscular involvement has not been detected, although the dermatologic lesions are still present despite different treatments reported to treat this condition (steroids, antimalarials, methotrexate, dapsone). However, an initial good response has been observed with thalidomide, a drug used increasingly in the dermatologic field. As far as we know, this case is the first of drug-induced amyopathic dermatomyositis.
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http://dx.doi.org/10.1097/00124743-200202000-00011 | DOI Listing |
JAAD Case Rep
December 2024
Department of Dermatology, University of Connecticut, Farmington, Connecticut.
Clin J Gastroenterol
December 2024
Division of Gastroenterology, Department of Internal Medicine, Tokyo Women's Medical University, 8-1 Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666, Japan.
The patient was diagnosed with amyopathic dermatomyositis complicated with interstitial pneumonia (IP) at age 35. She had been treated with prednisolone and maintained on tacrolimus (TAC) + azathioprine (AZA). Eight years later, she experienced epigastric pain, and esophagogastroduodenoscopy (EGD) led to a diagnosis of duodenal ulcer.
View Article and Find Full Text PDFAfr J Thorac Crit Care Med
October 2024
Department of Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
J Cutan Med Surg
November 2024
Michael G. DeGroote School of Medicine, Hamilton, ON, Canada.
Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by progressive muscle weakness and distinctive cutaneous findings. The exact incidence and prevalence of DM in the general population is largely unknown, and data on demographic and clinical features in patients in Canada are lacking. This study aimed to comprehensively evaluate the patients with DM in Southwestern Ontario, Canada.
View Article and Find Full Text PDFInfect Drug Resist
November 2024
Department of Respiratory and Critical Care Medicine, Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, People's Republic of China.
Objective: Interstitial lung diseases (ILDs) comprise a heterogeneous group of disorders characterized by inflammation and fibrosis of the pulmonary interstitium, posing significant challenges in identifying their underlying causes. Pneumocystis pneumonia (PCP) is the leading cause of ILD in people living with HIV (PLWH). In individuals with connective tissue diseases, ILD is a frequent complication with significant morbidity and mortality.
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