The objective of the present study was to investigate the effect of beta2-adrenoreceptor polymorphisms Arg16Gly and Gln27Glu as well as their relationship to the pulmonary function parameters, and the clinical presentation in patients with asthma and allergic rhinitis. Investigated polymorphisms were in linkage disequilibrium, therefore their effects should be evaluated collectively. Although no significant association could be found with the presence of asthma or allergic rhinitis in studied population, polymorphisms of beta2-adrenoreceptor can influence pulmonary function in these patients. These effects significantly differ between men and women, possibly indicating the effect of sex hormones on genetic regulation of pulmonary function.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
A Retrospective Comparison of Aeroallergen Sensitization Among Different Allergic Diseases in Guangzhou, China.
Mediators Inflamm
January 2025
Department of Otolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
Numerous studies have reported on the types of aeroallergen sensitization in various pediatric allergic diseases, but limited data compared the types of aeroallergen sensitization across different pediatric allergic diseases. The aim of this study is to explore the nature and significance of aeroallergen sensitization in diverse pediatric allergic conditions. A comparative analysis was carried out on aeroallergen sensitization in children suffering from allergic diseases who visited the Otolaryngology, Respiratory, and Dermatology Departments between January 2019 and December 2023.
View Article and Find Full Text PDFAssociation between allergic diseases and mucosal healing in ulcerative colitis.
Sci Rep
January 2025
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Allergic diseases and ulcerative colitis (UC) share pathophysiological similarities. This study aimed to investigate the unclear association between allergic diseases and mucosal healing (MH), an important factor in the prognosis of UC. We studied 289 Japanese patients with UC.
View Article and Find Full Text PDFEosinophilic Esophagitis-Related Food Impaction: Distinct Demographics, Interventions, and Promising Predictive Models.
Dig Dis Sci
January 2025
Division of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL, USA.
Background: Eosinophilic esophagitis (EoE) is an increasingly common cause of food impaction.
Aims: This study aims to provide a nationwide analysis of food impaction in patients with or without EoE diagnosis, concentrating on patient demographics, interventions, outcomes, and development of predictive machine-learning models.
Methods: A retrospective assessment was conducted using Nationwide Emergency Department Sample data from January 1, 2018, to December 31, 2019.
Machine learning-derived asthma and allergy trajectories in children: a systematic review and meta-analysis.
Eur Respir Rev
January 2025
Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Introduction: Numerous studies have characterised trajectories of asthma and allergy in children using machine learning, but with different techniques and mixed findings. The present work aimed to summarise the evidence and critically appraise the methodology.
Methods: 10 databases were searched.
The association of parental age at delivery with childhood allergic disease and the modified effect of breastfeeding.
Pediatr Allergy Immunol
January 2025
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Childhood allergic diseases are a global concern; quite limited studies have examined the impacts of parental age at delivery. This study aimed to explore the association between separate and combined parental age at delivery and childhood allergic diseases and whether adequate breastfeeding could modify this association.
Methods: This cross-sectional study sampled 15,976 children from Shanghai, China.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!