At present there is a steady rise in African sleeping sickness (trypanosomiasis) transmitted by the Tsetse fly, and which if left untreated, is fatal. Thanks to more than so years of neglect by research, our therapeutic repertoire is limited to medications with a high level of toxicity. Both WHO and international aid organizations are pushing hard for the development of new, more efficient drugs that can be readily applied in the field.
Download full-text PDF |
Source |
---|
Ann Behav Med
January 2025
Department of Psychology, Wayne State University, Detroit, MI, USA.
Background: Although sleep disparities contribute to racial health disparities, little is known about factors affecting sleep among African Americans. One such factor may be positive affect, which could impact sleep directly (direct effect hypothesis) or indirectly by buffering the effects of stress (stress buffering hypothesis).
Purpose: We tested the direct effect and stress buffering effects of positive affect on sleep at three levels (day, week, trait) in a sample of 210 older African American adults, ranging in age from 50 to 89 years old.
Animals (Basel)
March 2025
Lewyt College of Veterinary Medicine, Long Island University, New York, NY 11548, USA.
Trypanosomes are parasitic protozoa that cause severe diseases in humans and animals. The most important species of Trypanosmes include and . The most well-known human diseases are sleeping sickness in Africa and Chagas disease in South America.
View Article and Find Full Text PDFPLoS One
March 2025
Discipline of Pharmaceutical Sciences, School of Health Sciences, Westville Campus, University of KwaZulu-Natal, Durban, South Africa.
Introduction: There is an ongoing global upsurge of opioid misuse, fatal overdose and other related disorders, significantly affecting the African continent, due to resource-limited settings and poor epidemiological surveillance systems. This scoping review maps scientific evidence on epidemiological data on unlawful opioid use to identify knowledge gaps and policy shortcomings.
Method: The databases (PubMed, Scopus, Web of Sciences) and references were searched guided by Population, Concept, and Context (PCC) and PRISMA-ScR.
Laryngoscope Investig Otolaryngol
April 2025
Department of Otolaryngology-Head and Neck Surgery University of Texas Southwestern Medical Center and Division of Pediatric Otolaryngology, Children's Medical Center Dallas Texas USA.
Objectives: To determine the prevalence of positional obstructive sleep apnea (pOSA) in children undergoing adenotonsillectomy (AT) for OSA and to assess whether pOSA improves following AT.
Materials And Methods: Children with OSA diagnosed by polysomnography (PSG) at a tertiary care children's hospital were included. Data was collected on demographics, PSG parameters, and surgical management.
Eur Respir Rev
January 2025
Respiratory Research @ Alfred, School of Translational Medicine Monash University, Melbourne, Australia
Introduction: Social determinants of health (SDH), including age, sex, ethnicity, socioeconomic status and rurality, influence health outcomes. Clinical trials investigating antifibrotic agents for people with idiopathic pulmonary fibrosis (IPF) have been conducted in predominantly White and male populations; it is unclear whether other SDH have been considered. This study aimed to investigate active consideration and reporting of SDH in clinical trials of antifibrotic agents for people with IPF.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!
© LitMetric 2025. All rights reserved.