The reductive amination of aldehydes or ketones using Ph(2)SiH(2) or PhSiH(3) has been effectively promoted by the direct use of Bu(2)SnClH-pyridine N-oxide as a catalyst; this method has advantages in terms of its mild conditions and wide application to various carbonyls and amines, including aliphatic examples.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/b610614e | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Anti-Inflammatory Activity of Gomphrenin-Rich Fraction from L. f. Fruits.
Nutrients
December 2024
Division of Pharmaceutical Biotechnology, Department of Pharmaceutical Biology and Biotechnology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.
L. (Malabar spinach, Basellaceae), widely consumed as a leafy vegetable, produces dark-colored fruits rich in betacyanins, including rare 6-glycosylated derivatives called gomphrenins. Comprehensive studies on the anti-inflammatory potential of its gomphrenin fraction (A) and crude extract (B) employed various analytical and biological methods.
View Article and Find Full Text PDFReductive amination of triglycerides to fatty amines over a titanium oxide-supported Pt-Mo catalyst.
Org Biomol Chem
January 2025
Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531, Japan.
The reductive amination of naturally abundant triglycerides is a promising approach for the synthesis of fatty amines. However, existing catalytic systems for this transformation typically require harsh reaction conditions. Herein, we present a titanium oxide-supported platinum-molybdenum (Pt-Mo/TiO) catalyst that promotes the reductive amination of triglycerides to fatty amines.
View Article and Find Full Text PDFCost-effectiveness of budesonide-formoterol in maintenance therapy of asthma patients.
Rev Alerg Mex
December 2024
Master's in economics, HS Pharmacoeconomic Research, Mexico City, Mexico.
Article Synopsis
- The study aimed to analyze the cost-effectiveness of budesonide/formoterol compared to other asthma treatments at Mexico's National Institute for Respiratory Diseases.
- Budesonide/formoterol had a lower average cost per patient ($733.36 USD) compared to fluticasone/vilanterol ($767.24 USD), and it showed a significant reduction in exacerbations with an incremental cost-effectiveness ratio (ICER) of $613.31 USD for better management.
- Overall, budesonide/formoterol was found to be a very cost-effective treatment option, suggesting it could reduce healthcare costs associated with emergency visits and hospitalizations despite fewer exacerbations per patient.
Skeletal Muscle Relaxants and Their Impact on Intracranial Pressure in Neurosurgery.
Med Sci Monit
January 2025
Department of Rheumatology, University Clinical Hospital No. 1 Szczecin, Szczecin, Poland.
Skeletal muscle relaxants have their place in everyday use in numerous anesthesiological procedures, such as preparing a patient for surgery, supporting mechanical ventilation, and performing effective intubation. These drugs can be divided, based on their mechanism of action, into depolarizing skeletal relaxants, such as succinylcholine, and non-depolarizing skeletal muscle relaxants. Non-depolarizing agents are further categorized, based on their structure, into steroidal (eg, rocuronium) and benzylisoquinoline (eg, atracurium) compounds.
View Article and Find Full Text PDFMicrowave-Assisted Buchwald-Hartwig Double Amination: A Rapid and Promising Approach for the Synthesis of TADF Compounds.
ACS Omega
December 2024
Department of Chemistry, Faculty of Science, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
We herein report a microwave-assisted Buchwald-Hartwig double amination reaction to synthesize potential thermally activated delayed fluorescence compounds, forming C(sp)-N bonds between donor and acceptor units. Our approach reduces reaction times from 24 h to 10-30 min and achieves moderate to excellent yields, outperforming conventional heating methods. The method is compatible with various aryl bromides and secondary amines, including phenoxazine, phenothiazine, acridine, and carbazole.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!