Three patients with pregnancy-induced pancytopenia also exhibited variable features of sideroblastic anemia and amegakaryocytic thrombocytopenia. Treatment with anti-thymocyte globulin proved highly effective in two cases and a spontaneous remission occurred in the third. This illness is distinct from the more commonly reported incidental association of pregnancy with classic aplastic anemia. Its differentiation from myelodysplasia is also emphasized.
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http://dx.doi.org/10.1097/00000441-200610000-00008 | DOI Listing |
Intern Med
December 2017
Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Japan.
A 35-year-old woman with discoid lupus erythematosus (DLE) was admitted at 11 weeks' gestation with a persistent fever. Laboratory studies revealed pancytopenia, elevated liver enzymes, and hyperferritinemia. Bone marrow aspiration confirmed the diagnosis of hemophagocytic syndrome (HPS).
View Article and Find Full Text PDFJ Anaesthesiol Clin Pharmacol
July 2013
Department of Anesthesia, T.N.M.C. and B.YL. Nair Ch. Hospital, Mumbai, India.
Thrombocytopenia in pregnancy carries a major risk of feto-maternal morbidity and mortality. We present a case of hypocellular bone marrow with severe thrombocytopenia with pregnancy induced hypertension (PIH) for emergency lower segment cesarean section (LSCS). This disease is characterized by pancytopenia and hypocellular bone marrow with impaired morphology and maturation.
View Article and Find Full Text PDFSingapore Med J
October 2012
Department of Obstetrics and Gynaecology, Institute of Postgraduate Medicine and Research, Kolkata, West Bengal, India.
Introduction: We aimed to analyse the pregnancy outcome of women with extrahepatic portal vein obstruction.
Methods: This was a retrospective observational analysis conducted at the Institute of Postgraduate Medical Education and Research, Kolkata, India, between January 2007 and September 2009. A total of 41 pregnancies in 24 women were evaluated.
Zhonghua Fu Chan Ke Za Zhi
November 2011
Department of Obstetrics, Peking University People's Hospital, Beijing, China.
Objective: To investigate the etiology and clinical characteristics of pregnancy-emerged thrombocytopenia.
Methods: A retrospective analysis was conducted on clinical data of 159 pregnancies with thrombocytopenia, who were admitted to Peking University People's Hospital from January 2000 to January 2010. All the patients recruited in this study had no history of blood or immune system disease before pregnancy, and thrombocytopenia was the predominate clinical manifestation during pregnancy, with platelet counts less than 100 × 10(9)/L at least twice during pregnancy.
Am J Med Sci
October 2006
Methodist Academic Medicine Associates, The Methodist Hospital, Houston, Texas 77030, USA.
Three patients with pregnancy-induced pancytopenia also exhibited variable features of sideroblastic anemia and amegakaryocytic thrombocytopenia. Treatment with anti-thymocyte globulin proved highly effective in two cases and a spontaneous remission occurred in the third. This illness is distinct from the more commonly reported incidental association of pregnancy with classic aplastic anemia.
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