AI Article Synopsis
- The study focused on creating new organic compounds that include a sugar component, specifically synthesizing 2-phenylsulfonylhydrazono-3-(2',3',4',6'-tetra-O-acetyl-beta-d-glucopyranosyl)thiazolidine-4-one through the reaction of thiosemicarbazide and ethyl bromoacetate.
- The chemical structures of these compounds were identified using techniques like NMR spectroscopy, elemental analysis, and mass spectrometry.
- The resulting compounds displayed moderate levels of fungicidal and herbicidal activity in bioassays, and the study also explored how different solvents at reflux temperatures affected the reactions during synthesis.
Article Abstract
To develop novel biologically active organic compounds possessing a sugar moiety, a series of 2-phenylsulfonylhydrazono-3-(2',3',4',6'-tetra-O-acetyl-beta-d-glucopyranosyl)thiazolidine-4-one were synthesized via reaction of the thiosemicarbazide with ethyl bromoacetate. Their chemical structures were characterized by (1)H and (13)C NMR spectroscopy, elemental analysis and MS. The bioassay results indicated that some of these compound exhibit moderate fungicidal and herbicidal activities. Furthermore, the effect of various solvents at reflux temperature on the reactions of ethyl bromoacetate with the related thiosemicarbazides was investigated.
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| http://dx.doi.org/10.1016/j.carres.2006.09.010 | DOI Listing |
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