We studied modulation of the activities of the red nucleus (RN) neurons under to electrical stimulation of the orofacial motor cortex (OfM) in urethane-anesthetized rats. Of 57 neurons studied, 30 (53%) neurons modulated the firing patterns. The firing patterns of the RN neurons were classified into four types: an excitation (E) type (n=4), a long inhibition (LI) type (n=4), a short inhibition (SI) type (n=22), and a no-effect type (n=27). These modulated neurons were intermingled in the dorso-ventral part of the RN. Our results suggest that the RN neurons receive excitatory or inhibitory inputs from the OfM.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.brainres.2006.09.032 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Safety, efficacy, and mechanism of action of the temporo-masseteric nerve block.
J Oral Facial Pain Headache
June 2024
Department of Diagnostic Sciences, Rutgers School of Dental Medicine, Newark, NJ 07103, USA.
The objective of the study was to assess the utility and safety of Temporo-masseteric Nerve Block (TMNB), and to explore the mechanism for its apparent sustained pain relief. This manuscript describes, (1) a retrospective study evaluating pain reduction in patients who received the TMNB injection for the management of masticatory myogeneous pain (myalgia, per Diagnostic Criteria for Temporomandibular Disorders (DC/TMD criteria)), and (2) a motor nerve conduction study (NCS) of the temporalis and masseter, performed in the absence of signs or symptoms of TMD, before and after the TMNB injection. The results were as follows.
View Article and Find Full Text PDFEffectiveness of an 8-week neck exercise training on pain, jaw function, and oral health-related quality of life in women with chronic temporomandibular disorders: a randomized controlled trial.
J Oral Facial Pain Headache
March 2024
Faculty of business and Social Sciences, University of Applied Sciences, 49076 Osnabrück, Germany.
To test the effectiveness of an 8-week exercise program targeted to the neck muscles compared to manual therapy, and placebo treatments on orofacial pain intensity, jaw function, oral health-related quality of life (OHRQoL), and jaw range of motion (ROM) in women with Temporomandibular Disorders (TMD). In this randomized controlled trial, fifty-four women (between 18-45 years old) with a diagnosis of myofascial or mixed TMD according to the Research Diagnostic Criteria for TMD (RDC/TMD) were randomized into three groups: Neck motor control training (NTG), Manual Therapy Group (MTG), and Placebo Group (PG). All patients were evaluated with the Visual Analog Scale, Mandibular Function Impairment Questionnaire, Oral Health Impact Profile-14, and jaw Range of Motion (ROM) at baseline, immediately after treatment (after 8 weeks of treatment), one month, and three-month follow-up.
View Article and Find Full Text PDFGlycyrrhizic Acid Mitigates Haloperidol-Induced Neurotoxicity in SHSY-5Y Cells and Rats Via Activation of PI3k/Akt/Nrf2 Pathways.
Neurochem Res
January 2025
Department of Pharmacology, Central University of Punjab, Ghudda, Bhatinda, Punjab, 151401, India.
Antipsychotic medications are used to treat a psychological condition called 'Schizophrenia'. However, its long-term administration causes irregular involuntary motor movements, targeting the orofacial regions. Glycyrrhizic acid (GA) is a naturally occurring triterpene saponin glycoside obtained from the roots of the Glycyrrhiza glabra (liquorice) plant and well known for its antioxidant, antiapoptotic and neuroprotective abilities.
View Article and Find Full Text PDFBrain Network Alterations in Chronic Spinal Cord Injury: Multilayer Community Detection Approach.
Neurotrauma Rep
November 2024
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Neurological recovery in individuals with spinal cord injury (SCI) is multifaceted, involving mechanisms such as remyelination and perilesional spinal neuroplasticity, with cortical reorganization being one contributing factor. Cortical reorganization, in particular, can be evaluated through network (graph) analysis of interregional functional connectivity. This study aimed to investigate cortical reorganization patterns in persons with chronic SCI using a multilayer community detection approach on resting-state functional MRI data.
View Article and Find Full Text PDFCalifornia mice (Peromyscus californicus) adjust mouth movements for vocal production during early postnatal development.
BMC Biol
December 2024
College of Veterinary Medicine, Midwestern University, Glendale, AZ, USA.
Background: The order Rodentia is the largest group of mammals. Diversification of vocal communication has contributed to rodent radiation and allowed them to occupy diverse habitats and adopt different social systems. The mechanism by which efficient vocal sounds, which carry over surprisingly large distances, are generated is incompletely understood.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!