We report the first observation of laser seeding of the storage-ring microbunching instability. Above a threshold bunch current, the interaction of the beam and its radiation results in a coherent instability, observed as a series of stochastic bursts of coherent synchrotron radiation (CSR) at terahertz frequencies initiated by fluctuations in the beam density. We have observed that this effect can be seeded by imprinting an initial density modulation on the beam by means of laser "slicing." In such a situation, most of the bursts of CSR become synchronous with the pulses of the modulating laser and their average intensity scales exponentially with the current per bunch. We present detailed experimental observations of the seeding effect and a model of the phenomenon. This seeding mechanism also creates potential applications as a high-power source of CSR at terahertz frequencies.
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http://dx.doi.org/10.1103/PhysRevLett.97.074802 | DOI Listing |
New Phytol
January 2025
Section for Plant Biochemistry and Copenhagen Plant Science Centre, Department of Plant and Environmental Sciences, University of Copenhagen, 1871, Frederiksberg, Denmark.
Lupins are promising protein crops that accumulate toxic quinolizidine alkaloids (QAs) in the seeds, complicating their end-use. QAs are synthesized in green organs (leaves, stems, and pods) and a subset of them is transported to the seeds during fruit development. The exact sites of biosynthesis and accumulation remain unknown; however, mesophyll cells have been proposed as sources, and epidermal cells as sinks.
View Article and Find Full Text PDFJ Biomed Mater Res B Appl Biomater
January 2025
The Laboratory of Orthopaedic Tissue Regeneration & Orthobiologics, Department of Bioengineering, Clemson University, Clemson, South Carolina, USA.
The formation of fibrocartilage in microfracture (MFX) severely limits its long-term outlook. There is consensus in the scientific community that the placement of an appropriate scaffold in the MFX defect site can promote hyaline cartilage formation and improve therapeutic benefit. Accordingly, in this work, a novel natural biomaterial-the cartilage analog (CA)-which met criteria favorable for chondrogenesis, was evaluated in vitro to determine its candidacy as a potential MFX scaffold.
View Article and Find Full Text PDFNanomaterials (Basel)
December 2024
Quantum Nano Centre, Department of Chemical Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Laser conversion of commercial polymers to laser-induced graphene (LIG) using inexpensive and accessible CO lasers has enabled the rapid prototyping of promising electronic and electrochemical devices. Frequently used to pattern interdigitated supercapacitors, few approaches have been developed to pattern batteries-in particular, full cells. Herein, we report an LIG-based approach to a planar, interdigitated Li-S battery.
View Article and Find Full Text PDFBiomedicines
November 2024
ASA Campus Joint Laboratory, ASA Research Division, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy.
Background/objectives: Many lasers applied in skin rejuvenation protocols show emissions with wavelengths falling in the red or near-infrared (NIR) bands. To obtain further in vitro data on the potential therapeutic benefits regarding rejuvenation, we employed a 675 nm laser wavelength on cultured human dermal fibroblasts to understand the mechanisms involved in the skin rejuvenation process's signaling pathways by analyzing cytoskeletal proteins, extracellular matrix (ECM) components, and membrane integrins.
Methods: Normal human dermal fibroblasts (NHDFs) were irradiated with a 675 nm laser 24 h after seeding, and immunofluorescence microscopy and Western blotting were applied.
J Biomed Mater Res A
January 2025
Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland.
Bone tissue regeneration can be affected by various architectonical features of 3D porous scaffold, for example, pore size and shape, strut size, curvature, or porosity. However, the design of additively manufactured structures studied so far was based on uniform geometrical figures and unit cell structures, which often do not resemble the natural architecture of cancellous bone. Therefore, the aim of this study was to investigate the effect of architectonical features of additively manufactured (aka 3D printed) titanium scaffolds designed based on microtomographic scans of fragments of human femurs of individuals of different ages on in vitro response of human bone-derived mesenchymal stem cells (hMSC).
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