The main limiting factor in the consumption by humans of the velvet bean (Mucuna) is its relatively high content of L-Dihydroxyphenylalanine (L-Dopa), with levels as high as 9%. Conventional cooking methods used to transform raw velvet bean into an edible product are not sufficiently effective in reducing the levels of L-Dopa in adequate processing time. In this report, Mucuna beans were cooked by microwave, utilizing vapor and in water solutions at pH 3, 6, 7, 9 and 11. Cooking alkaline solutions were achieved using sodium hydroxide, potassium hydroxide, and calcium hydroxide. The acid pH was achieved through the use of HCl. The initial cooking time was fixed at 6 hrs. The processed bean samples were dried, ground and analyzed for L-Dopa and protein. The ground samples were further washed with boiling water for 0, 3 and 6 minutes, them dried and analyzed. None of the procedures evaluated was capable of eliminating L-Dopa from Mucuna beans. The Ca(OH)2 treatment at pH 9 which was washed with hot water produce a reduction of L-Dopa of 80.4%. There was not effect attributed to the alkaline ions. Reducing particle size appears to be most effective as it has been shown by other workers.
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Front Nutr
April 2024
Department of Chemistry, Indonesia University of Education, Bandung, Indonesia.
Introduction: Previous studies have shown that the velvet bean, an indigenous legume in Indonesia, possesses high protein content and bioactive compounds. However, the utilization of velvet beans in tempe production remains underexplored.
Methods: This study aims to address this research gap by investigating the physicochemical properties and sensory profiles of tempe made from velvet beans, both individually and in combination with soybean.
Clin Park Relat Disord
April 2024
Medical Corporation, Neshige Neurology Clinic, Kurume, Japan.
This retrospective review on patients with Parkinson's disease, focusing on using mucuna beans (MB), its dosing, and administration methods. Two hundred patients taking 1-3 g of MP dissolved in hot water daily orally. Besides, MB administration via enema may be viable, especially when oral L-dopa efficacy is insufficient.
View Article and Find Full Text PDFIntern Med
October 2024
Department of Neurology, Wakayama Medical University, Japan.
Objective Mucuna pruriens (MP) is a legume whose seeds contain levodopa (LD), which has potential therapeutic effects against Parkinson's disease (PD). However, further research is needed to thoroughly evaluate its efficacy and safety for treating this condition. In this study, we analyzed the pharmacokinetics of MP grown in Japan and investigated its mechanism of action in PD.
View Article and Find Full Text PDFTrop Anim Health Prod
September 2023
Faculty of Agricultural Sciences, University of Abomey-Calavi, Abomey-Calavi, Benin.
Ruminant production in West Africa faces both qualitative and quantitative feeding constraints during the dry season and animal diseases in smallholder farms. High-protein legume seeds can represent an alternative and sustainable feed that could enhance animal performance. The use of legume beans, limited by their anti-nutritional factor contents, can be improved through different detoxification methods.
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Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium.
In this study, the in vitro apparent rumen degradability of organic matter (ARDOM) and plant secondary metabolites (ARDPSM) of three tropical legumes (Mucuna pruriens, Canavalia ensiformis, and Leucaena leucocephala) were assessed. For this, 3 experiments were set up, i.e.
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