Estramustine binding protein in human benign prostatic hypertrophy.

Andrologia

Department of Urology, Shimane Medical University, Izumo-shi/Japan.

Published: February 1991

AI Article Synopsis

  • A radioimmunoassay (RIA) was used to measure estramustine binding protein (EMBP) levels in human benign prostatic hypertrophy (BPH) tissue.
  • EMBP concentration was significantly higher in the epithelium (10.7 ng/mg protein) compared to the stroma (2.9 ng/mg protein).
  • Among different BPH types, the glandular type had the highest EMBP levels (15.7 ng/mg protein), while the fibromuscular type had the lowest (10.8 ng/mg protein).

Article Abstract

Using a highly sensitive radioimmunoassay (RIA) of estramustine binding protein (EMBP) with the antibody raised against rat-EMBP, the concentration of EMBP in human benign prostatic hypertrophy (BPH) tissue was evaluated. Using mechanical separation procedure, EMBP was found significantly higher in the epithelium (10.7 ng/mg protein) than in the stroma (2.9 ng/mg protein). When human BPH was classified into glandular, fibromuscular and mixed type, the concentration of EMBP was the highest in glandular type (15.7 ng/mg protein) and the lowest in fibromuscular type (10.8 ng/mg protein).

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http://dx.doi.org/10.1111/j.1439-0272.1990.tb01990.xDOI Listing

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