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Potential Cisatracurium-Induced Malignant Hyperthermia: A Case Report.
Cureus
December 2024
Pulmonology and Critical Care, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Malignant hyperthermia is a pharmacogenetic disorder that manifests clinically as a hypermetabolic crisis when a patient with a mutation in the ryanodine or dihydropyridine receptor genes is exposed to neuromuscular blocking agents. Depolarizing neuromuscular agents are known to cause malignant hyperthermia, but cases caused by nondepolarizing agents are rarely reported. We present a case consistent with malignant hyperthermia after receipt of cisatracurium, a nondepolarizing anesthetic agent.
View Article and Find Full Text PDFTime to treat the climate and nature crisis as one indivisible global health emergency.
BMJ Oncol
October 2023
Centre for Global Health, University of Winchester, Winchester, UK.
C-reactive protein testing in primary care and antibiotic use in children with acute respiratory tract infections in Kyrgyzstan: an open-label, individually randomised, controlled trial.
Lancet Reg Health Eur
April 2025
The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Background: Addressing the global antibacterial resistance crisis and aligning with the Kyrgyz Ministry of Health's research priorities, this study assesses the efficacy and safety of C-reactive protein (CRP) testing to guide antibiotic prescriptions in children with acute respiratory tract infections (ARTI) in Kyrgyzstan.
Methods: In this open label individually randomised controlled trial, children aged 6 months to 12 years with ARTI in primary care settings were assigned to receive either standard care or standard care plus CRP testing. The study measured two primary outcomes: total antibiotic usage over a 14-day follow-up and caregiver-reported time to recovery.
The challenges faced by early-career international medical graduates in general practice and the opportunities for support: a mixed methods study.
Educ Prim Care
January 2025
College of Medicine and Health, University of Exeter, Exeter, UK.
Background: Recruiting and retaining International Medical Graduates (IMGs) has been identified as a key component in addressing the ongoing workforce crisis in general practice. However, research shows IMG General Practitioners (GPs) face unique challenges compared to their UK-trained counterparts, impacting their welfare, retention in the workforce, and ability to provide patient care.
Aim: This study examined the challenges facing early-career IMG GPs, the help and support they access and want to access, and their perceptions and utilisation of the help and support available.
A two-stage model of the fuzzy analytic hierarchy process and the fuzzy synthetic evaluation technique to prioritize sustainable sanitation services under uncertainty.
Sci Rep
January 2025
Department of Civil Engineering & Sustainable Structures, Technical University (Kadoorie), Jaffa Street, P.O. Box (7), Tulkarem, Palestine.
In the context of the Sustainable Development Goals (SDGs), which strive to ensure comprehensive access to fundamental water, sanitation, and hygiene (WASH) services, it is extremely imperative to prioritize communities in need and still disadvantaged. Moreover, tackling the worldwide sanitation crisis entails advancing the development of productive and sustainable sanitation systems and infrastructure. Sanitation planning is a multidimensional exercise encompassing multiple dimensions, stakeholders, and strategies, typically with conflicting objectives.
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