Aim: A positive correlation between maternal and cord-blood IgE levels is well documented for total IgEs, but not for specific IgEs. The difficulty in detecting specific cord-blood IgEs is due to their low concentrations, which hinder their dosage by low-sensitivity methods. The study aimed to correlate maternal and foetal specific IgEs against individual cow's milk proteins, detected by highly sensitive and specific techniques.
Methods: Cow's milk specific IgE detection was performed by chemiluminescence on 52 specimens of maternal and cord blood after cow's milk protein separation by 1D and 2D gel electrophoresis. Cow's milk protein (CMP) antigens were identified by mass spectrometry techniques.
Results: Specific IgEs for CMPs were found in 25/52 (48.1%) of maternal sera and in 19/52 (37%) of cord-blood sera. In order of decreasing frequency, the proteins found were BSA, IgG heavy chain, caseins and, in a single case, b-lactoglobulin. Positive cord-blood sera in all cases corresponded to a positive maternal result, and maternal and foetal immunoreactivity patterns were closely correlated. Moreover, in no case was there a positive cord-blood response with a negative maternal response.
Conclusion: The study demonstrates a close relationship between maternal and cord-blood specific IgE patterns. The phenomenon observed could provide a model to elucidate the general production method of foetal IgEs, which might only be produced in the presence of both the corresponding maternal IgE and the related allergen.
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http://dx.doi.org/10.1111/j.1399-3038.2006.00449.x | DOI Listing |
Food Microbiol
August 2025
Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350, Jouy-en-Josas, France. Electronic address:
Although isolating microorganisms from food microbiota may appear less challenging than from the gut or environmental sources, recovering all representative species from food remains a difficult task. Here, we showed by metagenomic analysis that several abundant species had escaped isolation in a previous study of ten cheeses, including several previously uncharacterized species. This highlights the ongoing challenge of achieving a comprehensive recovery of microbes from food.
View Article and Find Full Text PDFFood Res Int
April 2025
Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, No. 2 Yuan Ming Yuan West Road, Beijing 100193, China. Electronic address:
Bacillus subtilis is the primary strain used in fermented soy products. The applicant fermented soymilk with the laboratory strain B. subtilis BSNK-5 to enhance nutrient density.
View Article and Find Full Text PDFFood Res Int
April 2025
State Key Laboratory of Microbial Technology, Shandong University (Qingdao), Qingdao 266237, China; Binzhou Institute of Technology, Weiqiao-UCAS Science and Technology Park, Binzhou 256606, China.
Whey powder (WP), a dairy by-product with high biochemical oxygen demand (BOD) and chemical oxygen demand (COD), presents challenges due to its high production, low-value utilization, and environmental pollution. Based on the idea of turning waste into treasure, high-value use of WP was studied. Firstly, an engineered Bacillus subtilis co-expressing β-galactosidase (β-Gal) and L-arabinose isomerase (LAI) was constructed, which ultimately yielded 77.
View Article and Find Full Text PDFAnimal
February 2025
Business Economics Group, Wageningen University and Research, Hollandseweg 1, 6706 KN Wageningen, the Netherlands; Infectious Disease Epidemiology Group, Department of Animal Sciences, Wageningen University and Research, Droevendaalsesteeg 1, 6708 PB Wageningen, the Netherlands.
Reproductive hormones are regularly applied in dairy farms for cow fertility management regarding oestrus induction and treatment of reproductive diseases. The use of hormones in dairy farms needs to be explored with insight into the farmers' knowledge and attitude to obtain their reasoning behind their behaviour of hormone use. This study aimed to determine and associate dairy farmers' knowledge and attitude with their reproductive hormone use behaviour.
View Article and Find Full Text PDFFood Chem
March 2025
College of Chemistry, Changchun Normal University, Changchun 130032, PR China. Electronic address:
In this paper, a novel dual-potential ratiometric electrochemiluminescence (RECL) sensor was constructed and applied to the ultrasensitive detection of kanamycin (KAN). The RECL sensor was constructed using porous graphite phase carbon nitride (PCN) and luminol, which serve as the luminescent reagents at the cathode and anode, respectively. PCN not only functioned as the luminescent reagent for the cathode but also served as a carrier for the PtAu NPs.
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