Tin-free radical alkylation of ketones via N-silyloxy enamines.

Chem Commun (Camb)

Department of Chemistry and Center for Molecular Design and Synthesis, School of Molecular Science (BK-21), Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

Published: July 2006

The radical alkylation of ketones is achieved by their conversion into corresponding N-silyloxy enamines, followed by a radical reaction with alkyl halides bearing electron-withdrawing groups.

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Source
http://dx.doi.org/10.1039/b606295dDOI Listing

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