An unusual case of lymphedema tarda.

Med Sci Monit

Department of Plastic Reconstructive and Aesthetic Surgery, Zonguldak Karaelmas University Medical School, Kozlu/Zonguldak, Turkey.

Published: October 2006

Background: Lymphedema is the result of the equilibrium between the load to be cleared and the transport capacity of the clearing system. Lymphedema may be classified as primary or secondary, based on the underlying etiology. Primary lymphedema is an unusual disorder characterized by inadequate lymphatic drainage. Lymphedema tarda is a rare form of primary lymphedema.

Case Report: The case of lymphedema tarda documented here was chronic, progressive, and resistant to medical therapy and recurred several times after previous operations.

Conclusions: We performed two-staged operations and we recommend that the staged excisional procedures offers reliable long-term improvement and minimizes postoperative complications in chronic advanced lymphedema.

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Case reports of primary lymphedema tarda in South Korea: Two case reports of unilateral primary lymphedema tarda in lower extremities.

Medicine (Baltimore)

July 2023

Department of Rehabilitation Medicine, Rehabilitation Hospital, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Gyeongsangnam-do, Republic of Korea.

Rationale: Primary lymphedema is a form of lymphedema marked by a dysfunction of the lymphatic system without preceding medical conditions. One rare subtype of primary lymphedema, lymphedema tarda, occurs in those older than 35 years and is difficult to diagnose. This paper reports 2 cases of unilateral lymphedema tarda in the lower extremities in South Korea.

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Lymphoscintigraphic Bilateral Disease in Patients with Clinically Unilateral Primary Lower Limb Lymphedemas.

Lymphat Res Biol

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Services of Nuclear Medicine and of Dermatology, Multi-Disciplinary Clinic of Lymphology, Institute Jules Bordet, HIS-IZZ Hospitals and Universitary Hospital Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Primary lower limb lymphedemas (LLLEs; not present at birth) are classified as early- and late-onset. In both groups, distal lymphangiopathy distal dermal backflow (DDB) may be observed and, in clinically unilateral edema, abnormalities may be present at the level of contralateral limb. The aim of this study is to report the frequency of heterolateral lesions in these patients based on lymphoscintigraphic investigations (LySc).

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Elephantiasis (ENV) comprises an uncommon skin disease characterised by dermal fibrosis with hyperkeratotic, verrucous and papillomatous lesions that usually occur after chronic lymphoedema. We describe the case of a 56-year-old-man with neurofibromatosis type 1, no known surgical history, no chronic medication and no travel history, presenting with worsening non-pitting oedema and impressive foul-smelling mossy plaques and cobblestone-like nodules in both legs and feet, especially on the right, compatible with the diagnosis of ENV.

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Objective: Lymphedema is classified as primary or secondary according to the underlying cause. Primary lymphedema is hereditary and is considered a consequence of an inherited abnormality of the lymphatic system. Secondary lymphedema, however, is a consequence of lymphatic failure resulting from trauma, parasitic infection, or iatrogenic obstruction.

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