Background: The study was planned to determine the relationship of the Functional Rating Index (FRI) with disability, pain, and quality of life in patients with low back pain.
Material/methods: A total of 84 patients with low back pain, of whom 58 were women and 26 were men, with average age of 47.8 +/- 12.0 years participated in this study. The Functional Rating Index was used to determine the functional status of the patients. Disability was evaluated using the Roland-Morris Disability Questionnaire (RMQ), pain intensity was evaluated with the Visual Analog Scale (VAS), and the Short Form-36 (SF-36) was used to assess quality of life. The Pearson correlation coefficient was used for correlation of the FRI with the RMQ, VAS, and SF-36. The internal consistency for test-retest reproducibility of FRI was assessed with Cronbach's alpha.
Results: There was a strong positive correlation between the FRI and the RMQ (p < 0.05). It was found that an increase in severity of pain was associated with the FRI survey score (p < 0.05). There was a negative statistically significant correlation between the FRI and all parameters of SF-36 (p < 0.05). FRI demonstrated high internal consistency, with alpha = 0.960. The test-retest correlation was r = 0.926 (p = 0.000).
Conclusions: Our study reveals that the FRI, as a reliable instrument in assessing functional status, is associated with the RMQ, the VAS, and all items of the SF-36 in patients with LBP. It was concluded that changes in functional status were related to changes in disability, pain, and quality of life.
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Phys Ther
January 2025
IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Importance: Rotator cuff tendinopathy represents the most prevalent cause of shoulder pain, the third most common musculoskeletal disorder after low back pain and knee pain.
Objective: The objective of this study was to determine the effectiveness of corticosteroid injection(s), alone or in combination with anesthetic injection or any other physical therapist interventions, compared to physical therapist interventions alone in adults with rotator cuff tendinopathy.
Design: This study was a systematic review and meta-analysis of randomized controlled trials.
JAMA Netw Open
January 2025
Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Importance: Secondary lymphedema is a common, harmful side effect of breast cancer treatment. Robust risk models that are externally validated are needed to facilitate clinical translation. A published risk model used 5 accessible clinical factors to predict the development of breast cancer-related lymphedema; this model included a patient's mammographic breast density as a novel predictive factor.
View Article and Find Full Text PDFHealth Econ Rev
January 2025
Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Bari, Italy.
Background: In their interesting systematic review, Gallehzan et al. quoted our article Cost-utility analysis of teriflunomide in naïve vs. previously treated patients with relapsing-remitting multiple sclerosis (RRMS) in Italy.
View Article and Find Full Text PDFReprod Sci
January 2025
Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, 601 Huangpu Rd, Guangzhou, 510632, PR China.
High-fructose and high-fat diet (HFHFD) has been associated with impaired spermatogenesis, leading to decreased sperm quality and increased male infertility, with similar effects observed in offspring. Cyanidin-3-O-glucoside (C3G), a recognized food antioxidant, has shown promise in protecting in male reproduction and modulating epigenetic modifications. However, its potential role in ameliorating intergenerational inheritance induced by HFHFD remains underexplored.
View Article and Find Full Text PDFPlant Mol Biol
January 2025
School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan, 411201, China.
Deficiency or excess of mineral elements in the environment is a primary factor limiting crop yields and nutritional quality. Lotus (Nelumbo nucifera) is an important aquatic crop in Asia, but the mechanism for accumulating mineral nutrients and coping with nutrient deficiency/excess is still largely unknown. Here, we identified NnMTP10, a member of the cation diffusion facilitator family, by screening the cDNA library of lotus.
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