Evaluating new therapeutic agents for invasive aspergillosis requires animal models that are reproducible among different laboratories. We therefore evaluated a murine model of aerosol infection in two independent laboratories and found a high level of both intra- and interlaboratory reproducibility of survival, fungal burden over time, and the efficacy of liposomal amphotericin B.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1610079PMC
http://dx.doi.org/10.1128/AAC.00787-06DOI Listing

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