AI Article Synopsis

  • Rapid diagnosis in neuropathology relies on techniques like crush smear preparation and frozen section analysis during surgeries.
  • Microwave technology has recently been adopted for faster tissue processing and staining, with automated options now available.
  • A study explored using a domestic microwave (costing around Rs. 5000) for urgent histoprocessing in small labs, proving to be a more economical alternative to traditional methods without compromising the quality of tissue sections.

Article Abstract

Rapid diagnosis of histopathological material is becoming increasingly desirable. In neuropathology, crush smear preparation and frozen section diagnosis of tissues removed during operative procedures, have remained as essential tools for rapid diagnosis. Microwave technology has been introduced into the field of tissue processing and staining in past decade. Now-a-days even automated microwave assisted rapid tissue processors are available. In our study we have analysed the use of a domestic microwave (cost approximately Rs.5000) for urgent histoprocessing (30 minutes). This could be useful in small laboratories or the ones which are in the phase of establishing the department as the procedure is much more economical than obtaining a frozen section (which requires a cryostat worth 3-6 lakhs) and the interpretation of the section obtained does not require any extra experience as these resemble the routinely processed tissue sections. The advantages and limitations of the procedure have been discussed.

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