Gordon Yu Hoi Chiu Echocardiographic Laboratory, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Published: October 2006
AI Article Synopsis
Article Abstract
Objective: We sought to determine the prognostic value of myocardial contrast echocardiography (MCE) in patients with known or suggested coronary artery disease compared with technetium-99m sestamibi single photon emission computed tomography (SPECT)-myocardial perfusion imaging (MPI).
Background: The prognostic value of SPECT-MPI is well established for patients with coronary artery disease. It is less well defined by MCE.
Methods: In all, 51 consecutive patients with suggested coronary artery disease prospectively underwent MCE and SPECT-MPI at baseline and after dipyridamole infusion. MCE and SPECT-MPI were independently analyzed for myocardial perfusion. Cardiac events during the follow-up period were determined, and event-free survival was calculated for MCE and SPECT-MPI techniques separately.
Results: MCE (log rank P < .005) and SPECT-MPI (log rank P < .05) demonstrated equivalent event-free survival. The negative predictive value for events for both MCE and SPECT-MPI was 100%.
Conclusion: MCE accurately classifies patients at risk for cardiac events and provides prognostic information comparable with validated SPECT-MPI techniques.
There have been no reports on prognostic prediction and risk stratification based on stress phase bandwidth (SPBW), or a left ventricular (LV) mechanical dyssynchrony index, in patients with known or suspected stable coronary artery disease (CAD) at low or intermediate risk of major cardiac events (MCEs) using the J-ACCESS risk model. We retrospectively investigated 4,996 consecutive patients with known or suspected CAD who underwent rest Tl and stress Tc-tetrofosmin electrocardiogram (ECG)-gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) and followed up for 3 years to confirm their prognosis. MCE risk over 3 years was estimated using an equation based on that used in the J-ACCESS study.
Objective: We sought to determine the prognostic value of myocardial contrast echocardiography (MCE) in patients with known or suggested coronary artery disease compared with technetium-99m sestamibi single photon emission computed tomography (SPECT)-myocardial perfusion imaging (MPI).
Background: The prognostic value of SPECT-MPI is well established for patients with coronary artery disease. It is less well defined by MCE.
