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http://dx.doi.org/10.1080/15459620600920598 | DOI Listing |
Am J Lifestyle Med
August 2024
Spaulding Rehabilitation Hospital, Charlestown, MA, USA (BF).
The Donald A. Pegg Leadership Award, established in 2016 by the American College of Lifestyle Medicine (ACLM), recognizes emerging leaders in Lifestyle Medicine by awarding key seed funding to support Lifestyle Medicine Interest Groups (LMIGs) and conference support to attend the ACLM's annual conference. Through its generous support of students and LMIGs, the Pegg Award has been instrumental in catalyzing transformations in medical education, promoting awareness and integration of key Lifestyle Medicine principles into curricula.
View Article and Find Full Text PDFJ Surg Oncol
November 2024
Department of Surgery, Icahn School of Medicine at Mount Sinai, Manhattan, New York, USA.
Background: Neoadjuvant chemotherapy (NC) for early pancreatic ductal adenocarcinoma (PDAC) remains controversial. We investigate the adoption of NC and its impact on survival in clinical T1 (cT1) PDAC.
Methods: National Cancer Database (2006-2017) was reviewed for cT1 PDAC.
Brain Sci
July 2024
McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, ON K1G 5Z3, Canada.
Reports suggest possible risks of adverse cardiovascular reactions, including heart failure, associated with non-ergot dopamine agonist (DA) use in Parkinson's disease (PD). The objectives of our review were to evaluate the risk of heart failure and other adverse cardiovascular reactions in PD patients who received a non-ergot DA compared with other anti-PD pharmacological interventions, placebo, or no intervention. Studies were identified via searches of six bibliographic databases.
View Article and Find Full Text PDFPlant Biotechnol J
November 2024
USDA-ARS Appalachian Fruit Research Station, Kearneysville, West Virginia, USA.
Cis-regulatory elements (CREs) are integral to the spatiotemporal and quantitative expression dynamics of target genes, thus directly influencing phenotypic variation and evolution. However, many of these CREs become highly susceptible to transcriptional silencing when in a transgenic state, particularly when organised as tandem repeats. We investigated the mechanism of this phenomenon and found that three of the six selected flower-specific CREs were prone to transcriptional silencing when in a transgenic context.
View Article and Find Full Text PDFJACC Heart Fail
July 2024
Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Background: High-density lipoprotein (HDL) is commonly characterized by its cholesterol concentration (HDL-C) and inverse association with atherosclerotic cardiovascular disease.
Objectives: The authors sought to evaluate the association of HDL particle concentration (HDL-P), HDL particle size (HDL-size), HDL-C, and cholesterol content per particle (HDL-C/HDL-P) with risk of overall heart failure (HF) and subtypes.
Methods: Participants from the Atherosclerosis Risk In Communities Study, Dallas Heart Study, Multi-Ethnic Study of Atherosclerosis, and Prevention of Renal and Vascular End-stage Disease studies without HF history were included.
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