Background: Smegma is widely believed to cause penile, cervical and prostate cancer. This nearly ubiquitous myth continues to permeate the medical literature despite a lack of valid supportive evidence.
Methods: A historical perspective of medical ideas pertaining to smegma is provided, and the original studies in both animals and humans are reanalysed using the appropriate statistical methods.
Results: Evidence supporting the role of smegma as a carcinogen is found wanting.
Conclusions: Assertions that smegma is carcinogenic cannot be justified on scientific grounds.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/j.1468-3083.2006.01653.x | DOI Listing |
Cureus
August 2022
Public Health, Amrita Institute of Medical Sciences & Research Center, Kochi, IND.
Smegma pearls, also called smegmomas, are a natural secretion composed of epithelial cells, protein, and fat. Smegma pearls are not carcinogenic and do not induce damage or irritation. Despite the frequent occurrence of smegma pearls in uncircumcised children, no case among circumcised patients was reported.
View Article and Find Full Text PDFCureus
December 2021
Family Medicine, Tower Health Medical Group, Reading Hospital, Reading, USA.
Smegma pearls can cause diagnostic dilemmas for pediatricians who are unfamiliar with this condition leading to unnecessary investigations and referrals. Despite the common occurrence of smegma pearls in uncircumcised young boys, it is not often reported in the literature. Smegma is a normal secretion consisting of desquamated epithelial cells, fat, and protein.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
October 2006
Department of Pediatrics, Michigan State University School of Human Medicine, Marquette, MI, USA.
Background: Smegma is widely believed to cause penile, cervical and prostate cancer. This nearly ubiquitous myth continues to permeate the medical literature despite a lack of valid supportive evidence.
Methods: A historical perspective of medical ideas pertaining to smegma is provided, and the original studies in both animals and humans are reanalysed using the appropriate statistical methods.
Ned Tijdschr Geneeskd
August 1995
Rijksuniversiteit, vakgroep Huisartsgeneeskunde, Leiden.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!