Aim: To assess the effectiveness of laparoscopic ovarian drilling (LOD) in women with polycystic ovary syndrome (PCOS) with normal and high body mass indices (BMIs).
Methods: We investigated the effects of LOD process on two different groups of Turkish women with normal (n = 13) and high (n = 12) body mass indices. Three-puncture laparoscopy was performed under general anesthesia. Luteinizing hormone (LH), follicle-stimulating hormone (FSH), dehydroepiandrosterone-sulfate (DHEAS) and total testosterone (total T) levels were measured one menstrual cycle before the operation (in early follicular phase defined as day 3 of the menstrual cycle) and one menstrual cycle after the operation (in early follicular phase defined as day 3 of the menstrual cycle).
Results: Ovarian drilling had a positive effect on FSH increase and DHEAS, total testosterone and LH/FSH ratio decrease; but BMI levels had no effect on these hormonal changes, respectively (F = 0.343, P = 0564) (F = 0.790, P = 0383) (F = 0.083, P = 0776) and (F = 0.816, P = 0376). Ovarian drilling had a positive effect on LH decrease and BMIs were effective on this change (F = 6.946, P < 0.05). LH decrease in the group with normal BMI was significantly higher than the obese group with high BMI. Ten of 13 women with normal BMI (76.9%) and eight of 12 women with high BMI (66.6%) started to see regular menses 2 to 3 months after the procedure.
Conclusion: Ovarian drilling is an effective procedure on PCOS. Women with lower BMI may benefit more from the procedure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1447-0756.2006.00446.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Transvaginal ovarian drilling for polycystic ovary syndrome prior to in vitro fertilization dramatically improves embryo yield, implantation, and ongoing pregnancy rates.
J Assist Reprod Genet
December 2024
Department of Obstetrics and Gynecology, Westchester Medical Center, New York Medical College, 35 Sunshine Cottage Road, Valhalla, NY, 10595, USA.
Purpose: To evaluate the effect of transvaginal ovarian drilling (TVOD) on IVF outcomes in subjects with clomiphene-resistant PCOS and a history of IVF failure.
Methods: Between 2008 and 2011, 19 subjects with sonographically PCOS and a history of failure to ovulate to high-dose clomiphene citrate were prospectively followed and underwent TVOD at a university hospital-based IVF program.
Results: In 15 subjects who underwent 30 fresh paired IVF cycles TVOD resulted in a significantly higher number of oocytes retrieved (7.
Fertiloscopy and its place in the gynaecologist's armamentarium.
Aust N Z J Obstet Gynaecol
November 2024
Graduate School of Medicine, Faculty of Science Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia.
Background: Infertility is a prevalent issue worldwide. Current investigation of female pelvic infertility uses transabdominal laparoscopy, exposing patients to its associated risks. An alternative method is fertiloscopy, comprising hysteroscopy, tubal dye studies, and transvaginal hydrolaparoscopy (TVHL), falling under the broader category of VNOTES.
View Article and Find Full Text PDFOngoing Clinical Trials for Polycystic Ovarian Syndrome (PCOS) Afflicted Infertility in Women: A Narrative Review.
Rev Recent Clin Trials
October 2024
Department of Clinical Research, Sharda School of Allied Health Science, Sharda University Greater Noida, 201310, India.
Article Synopsis
- Polycystic Ovary Syndrome (PCOS) is a common hormonal disorder in women of reproductive age, linked to issues like infertility, irregular menstrual cycles, and excess male hormones (hyperandrogenism).
- The exact causes of PCOS are not fully understood, but factors like insulin resistance, obesity, and genetics are believed to play a role. The condition can present differently in each individual, complicating diagnosis.
- Current treatment options for PCOS-related infertility include medications like clomiphene citrate and metformin, as well as lifestyle changes, with ongoing clinical trials exploring new therapies.
Pulmonary hydatid cyst emergence post laparoscopic ovarian drilling in a clear preoperative chest: A novel case report.
Radiol Case Rep
December 2024
Internal Medicine Department, University of Baghdad, College of Medicine, Baghdad, Iraq.
Article Synopsis
- * A 24-year-old woman developed a persistent cough and chest discomfort three weeks after laparoscopic ovarian surgery, leading to the discovery of a hydatid cyst via chest X-ray and CT scans.
- * Following the surgical removal of the cyst and subsequent antiparasitic treatment with albendazole, the patient had a smooth recovery with no symptoms during follow-up.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!