Chromobacterium violaceum produces autoinducers, including homoserine lactones (HSLs), for genetic regulation. Among the seven HSLs derived from C. violaceum we evaluated, only C(12)-HSL stimulated the production of inflammatory cytokines in mammalian monocytic cell lines through the activation of the NF-kappaB signaling pathway besides their quorum-sensing role, like 3-oxo-C(12)-HSL from Pseudomonas aeruginosa.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698062 | PMC |
| http://dx.doi.org/10.1128/IAI.00038-06 | DOI Listing |
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