Objective: To determine an ideal recipe and technique for making of compound Rhizoma Acori Tatarinowii naphtha emulsion (CRATNE) , diameter for the granule in 10 to approximately 20 microm.
Methods: CRATNE was made by two-step emulsification and the recipe was evaluated to investigate the effect of diameter for the granule on stir time and stir speed and oxygen ventilated.
Results: The percentages of diameter for the granule in 10 to approximately 20 microm was 72%. Emulsion was made on recipe No. 4 [ Rhizoma Acori Tatarimowii naphtha (ml): liquid paraffin (ml): Sorbian monooleate (g): 0.5% gelatin solution (ml): distilled water (ml) is 1.05: 16: 7: 1: 16] and compound emulsion is made on recipe No. 4 [fore emulsion (g): Tween-80 (g): distilled water (ml) is 10: 1: 9]. Recipe No. 4 was the best one if stiring at low speed through magnetic force mixer was used. Stir time was 1 min. The oxygen was ventilated with a flow rate of 2 L/min for CRATNE. Ventilation time was 1 h. The percentages of diameter for the granule in 10 to approximately 12 microm increased from 72% to 79%. was type W/O/W.
Conclusion: The diameter of CRATNE for the granule is in 10 to approximately 20 microm, can be made following above-mentioned methods.
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