AI Article Synopsis

  • The study analyzed data on stillbirth cases from 2000-2004, focusing on the role of infections in intrauterine fetal death (IFD).
  • In 768 stillbirth cases, 591 involved IFD, with a majority related to preterm labor, and 24.4% linked to congenital malformations.
  • The research highlighted that infectious causes were present in 17.1% of cases, while unknown factors accounted for a significant 34.3%, indicating a need for further exploration of unexplained IFD causes.

Article Abstract

We have done retrospective analysis of stillbirth. The aim of our study was to investigate specific role of infections in stillbirth on the basis of archival data of Acad. Chachava Research Institute of Perinatal Medicine, Obstetrics and Gynecology. In 768 cases of stillbirth over a period 2000-2004, in 591 cases occurred intrauterine fetal death (IFD) (77%). In 85% of cases it was related to the preterm labor. Most frequently IFD occurred in relation to the congenital fetal malformations (24.4%). In 12.1% of cases the cause of the structural anomalies in fetuses was unknown. Infectious pathology occurred in 17.1% of cases and in 15.4%--preeclampsia. Significantly high percent are related to the unknown reasons that lead to the IFD (34.3%). Study addressing the risk factors of the intrauterine fetal death IFD revealed that odds ratio (OR) is the most high for fetal malformation--36.34; for preeclampsia--5.15; for infectious pathology--10.93; so it holds the third place after the fetal maldevelopment and preeclampsia.

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