FOXO3A and FOXO1A are excellent candidate genes for the development of premature ovarian failure and have not been analyzed previously in POF patients. Potentially causal mutations in FOXO3A (2/90; 2.2%) and FOXO1A (1/90; 1.1%) were identified in POF patients; however, the pathological role of these mutations will be determined only by screening increased numbers of patients and controls, or by functional studies.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.fertnstert.2006.03.054 | DOI Listing |
Publication Analysis
Top Keywords
foxo3a foxo1a
8
premature ovarian
8
ovarian failure
8
pof patients
8
mutational screening
4
screening foxo3a
4
foxo1a women
4
women premature
4
failure foxo3a
4
foxo1a excellent
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!