Objectives: Evaluation of the performance of the EMIT 2000 Tacrolimus assay on the Abbott Architect c8000 analyzer.

Design And Methods: Imprecision studies were performed and patient samples were assayed by EMIT assay and by LC-MS/MS.

Results: Limit of quantification was established at 2.8 microg/L. A positive bias of 17.5% between results measured on EMIT and on LC-MS/MS was detected.

Conclusions: EMIT 2000 Tacrolimus assay is suitable for automated analyses of Tacrolimus on the Architect c8000.

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http://dx.doi.org/10.1016/j.clinbiochem.2006.06.011DOI Listing

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