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Spontaneous Heterotopic Pregnancy: A Case Report of a Rare and Critical Obstetric Condition.
Cureus
January 2025
Obstetrics and Gynecology, Al Thagher General Hospital, Jeddah, SAU.
Heterotopic pregnancy is defined as the concurrent presence of both an intrauterine pregnancy and an extrauterine (typically ectopic) pregnancy. This report presents the case of a 36-year-old female patient who presented to the emergency department with lower abdominal pain. A comprehensive evaluation, including transabdominal and transvaginal ultrasound imaging, revealed a heterotopic pregnancy at an estimated gestational age of six weeks and two days.
View Article and Find Full Text PDFSequenceCraft: machine learning-based resource for exploratory analysis of RNA-cleaving deoxyribozymes.
BMC Bioinformatics
January 2025
International Institute "Solution Chemistry of Advanced Materials and Technologies", ITMO University, Saint-Petersburg, Russian Federation, 191002.
Background: Deoxyribozymes or DNAzymes represent artificial short DNA sequences bearing many catalytic properties. In particular, DNAzymes able to cleave RNA sequences have a huge potential in gene therapy and sequence-specific analytic detection of disease markers. This activity is provided by catalytic cores able to perform site-specific hydrolysis of the phosphodiester bond of an RNA substrate.
View Article and Find Full Text PDFEffects of nurse-home visiting on intimate partner violence and maternal income, mental health and self-efficacy by 24 months postpartum: a randomised controlled trial (British Columbia Healthy Connections Project).
BMJ Open
January 2025
Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.
Objective: To evaluate the impact of Nurse-Family Partnership (NFP), a home-visiting programme, on exploratory maternal outcomes in British Columbia (BC), Canada.
Design: Pragmatic, parallel arm, randomised controlled trial conducted October 2013-November 2019. Random allocation of participants (1:1) to comparison (existing services) or NFP (plus existing services).
Transvaginal Evisceration in a Patient With Rectovaginal Prolapse: A Twist in the Tale.
Cureus
December 2024
General Surgery, Hospital do Espírito Santo de Évora, Évora, PRT.
Transvaginal evisceration is a rare, potentially life-threatening condition involving herniation of intra-abdominal contents, typically the small bowel, through a defect in the vaginal wall. Most commonly observed in postmenopausal women with a history of pelvic surgery or trauma, it necessitates prompt surgical intervention. We report a unique case of transvaginal evisceration in a 67-year-old postmenopausal female with rectovaginal prolapse following minor trauma.
View Article and Find Full Text PDFBehavior and emotion regulation of socially inhibited individuals in uncomfortable social situations: A mixed methods study.
Int J Clin Health Psychol
December 2024
Department of Medical and Clinical Psychology, CoRPS - Center of Research on Psychological disorders and Somatic diseases, Tilburg University, Netherlands.
The current study aimed to identify patterns of emotion regulation and behaviors in specific uncomfortable situations using a sequential exploratory mixed methods design and to examine how the trait social inhibition (SI) is related to these patterns. The sample (N = 451, 66% female, M = 34 (SD=17.2)) collected in 2016-2017 completed the social inhibition questionnaire (SIQ15) and open-ended questions on self-indicated uncomfortable situations and the regulation of emotions and behaviors in those situations.
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