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Nature
January 2025
Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Glioblastoma (GBM) infiltrates the brain and can be synaptically innervated by neurons, which drives tumor progression. Synaptic inputs onto GBM cells identified so far are largely short-range and glutamatergic. The extent of GBM integration into the brain-wide neuronal circuitry remains unclear.
View Article and Find Full Text PDFJ Health Popul Nutr
January 2025
Community Health Nursing Department, Faculty of Nursing, Cairo University, Cairo, 11562, Egypt.
Background: Rabies spreads to people and animals via saliva, usually through bites, scratches, or direct contact with mucosa (e.g. eyes, mouth, or open wounds).
View Article and Find Full Text PDFBMC Public Health
January 2025
Sydani Institute for Research and Innovation, Sydani Group, Abuja, Nigeria.
Background: Rabies remains a significant public health concern in Nigeria, particularly in rural areas with limited awareness and resources. Gombe State is recognized as a rabies hotspot, facing challenges in controlling the spread of the disease. This study aimed to assess and compare the knowledge and prevention practices related to rabies among community members in hotspot and non-hotspot areas of Gombe State.
View Article and Find Full Text PDFInt J Food Microbiol
January 2025
Anses, Nancy Laboratory for Rabies and Wildlife, Malzéville, France.
Cystic and alveolar echinococcosis are severe zoonotic diseases characterized by long asymptomatic periods lasting months or years. Viable Echinococcus spp. eggs released into the environment through the feces of canids can infect humans through accidental ingestion via hand-to-mouth contact or consumption of contaminated food or water.
View Article and Find Full Text PDFJ Extracell Vesicles
January 2025
Shanghai Jiao Tong University Affiliated Sixth People's Hospital, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Extracellular vesicles (EVs) have shown great potential for treating various diseases. Translating EVs-based therapy from bench to bedside remains challenging due to inefficient delivery of EVs to the injured area and lack of techniques to visualize the entire targeting process. Here we developed a dopamine surface functionalization platform that facilitates easy and simultaneous conjugation of targeting peptide and multi-mode imaging probes to the surface of EVs.
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